DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP705A23

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_188649.1	Gene:	CYP705A23 / 821557	AraportID:	AT3G20140	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	136/559 - (24%)
Similarity:	247/559 - (44%)	Gaps:	93/559 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LVLVILYLC-------ERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFEL 86
            |:.::|.||       .:...|..|. ||.|..||.:|:|..|.:...|||||||:.:||.:..|
plant    17 LLCILLLLCYPLFFKKPKVSQDGFGL-PPSPLSLPIIGHLHLLFSNLTHKSLQKLSSKYGPLLYL 80

  Fly    87 KMGRVPTVVLSDAALVRDFFR-RDV---MTGRAPLYLTHGIMGGFGIICA-QEDIWRHARRETID 146
            ::..||.:.:|.|::..:.|| .||   ..|..|:..:. ::|.||...| ..|.|:..::..:.
plant    81 RIFNVPIIFVSSASVAYEIFRGHDVNISFRGNPPIEESL-LVGSFGFFTAPYGDYWKFMKKVMVT 144

  Fly   147 WLKALGMTRRPGELRA-RLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVF 210
            .|......:|...:|| .|||.....:|:.::      |:|.......:..::.|    |..::.
plant   145 KLLGPQALQRSRGIRADALERFYMNLLDKAMK------KESVEIGKETMKLIYDS----ICKMIM 199

  Fly   211 GITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIV 275
            |             :...||..:...|.|:|.                   |..|.|..|:...|
plant   200 G-------------RNFSEENGEAERVRGLVT-------------------ESTALTKKIFMANV 232

  Fly   276 EACGQRLKEKQKVFKELQEQKRLQRQL-EKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPEC 339
                        :.|.|   |:|...| :||.:..|...|...|:...:.:::.::::|......
plant   233 ------------LHKPL---KKLGISLFKKEIMDVSNSFDELLERFLVEHEEKLNEDQDMDMMGV 282

  Fly   340 ILEHFLAVRDTDSQLYCD---DQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRL-HELL 400
            :|   .|.||.:::  |.   :.::.|..||..||.|||....:|.:..:..:.:...:: .|:.
plant   283 LL---AACRDKNAE--CKITRNHIKSLFVDLVVAGTDTSRHATQWTMAEIINKPKVLEKVREEIY 342

  Fly   401 LPLGPSPTLEE--LEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWA 463
            ..:|.:..::|  |..|.||:|.:.|.:|:....|| .....:|.|.||.:::...:.:|.:.:|
plant   343 SVVGRTRLVQETDLPSLPYLQATVKEGLRLHPPGPL-FARTAREGFSVGGFYVPENTPLVVNAYA 406

  Fly   464 IHMDPVAFPEPEEFRPERFLTA--DGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRF 526
            :..||.::.:|.||:|||||.:  :...:...::|||.||.|.|||..:|.:::....|.:::.|
plant   407 MMRDPGSWEDPNEFKPERFLGSGKEDEREHGLKYIPFGSGRRGCPGINLAYILVGTAIGVMVQCF 471

  Fly   527 HLELPSGTEVDMAGESGITLTPTPHMLRF-----TKLPA 560
            ..:: .|.:|:|....|..:....|.|:.     |::|:
plant   472 DWKI-KGNKVNMEEARGSLVLTMAHPLKCIPVARTQIPS 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	128/520 (25%)
CYP705A23	NP_188649.1	p450	26..504	CDD:386267	130/543 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050