DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment phm and CYP78A6

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_182189.1	Gene:	CYP78A6 / 819278	AraportID:	AT2G46660	Length:	530	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	110/527 - (20%)
Similarity:	204/527 - (38%)	Gaps:	94/527 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGG--IFELKMGRVPTVVLSDAALVRDFFRRDVMT 112
            |||.|.|.:|.:..:.:...|:.:...|:::|.  :....:|....:|..:..:.::.....|..
plant    72 PGPKGFPLVGSMSLMSSTLAHRRIADAAEKFGAKRLMAFSLGETRVIVTCNPDVAKEILNSPVFA 136

  Fly   113 GRAPLYLTHGIMGGFGIICAQEDI-WRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECV 176
            .|......:.:|....|..|...: ||..||...:.|.:....|     ||..:||:..  .:.|
plant   137 DRPVKESAYSLMFNRAIGFAPHGVYWRTLRRIASNHLFSTKQIR-----RAETQRRVIS--SQMV 194

  Fly   177 RLFDTE-AKKSC-ASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSG 239
            ...:.: :.:.| ..|:....:|::.:.:     |||..|:. :.:.:.|:.:.|||..|:|...
plant   195 EFLEKQSSNEPCFVRELLKTASLNNMMCS-----VFGQEYEL-EKNHVELREMVEEGYDLLGTLN 253

  Fly   240 VVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEK 304
            ..:.||||.                           |...|||:.:....  :.:..|...::..
plant   254 WTDHLPWLS---------------------------EFDPQRLRSRCSTL--VPKVNRFVSRIIS 289

  Fly   305 EQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFG 369
            |...|:.:.                       |...::..|::..:|.  ..|..:..:|.::..
plant   290 EHRNQTGDL-----------------------PRDFVDVLLSLHGSDK--LSDPDIIAVLWEMIF 329

  Fly   370 AGVDTSLATLRWFLLYLAREQRCQRRL-HELLLPLGPSPTLEE--LEPLAYLRACISETMRIRSV 431
            .|.||....:.|.|..:......|..: :||...:|.|..|:|  |..|.||.|.:.|.:|:...
plant   330 RGTDTVAVLIEWILARMVLHPDMQSTVQNELDQVVGKSRALDESDLASLPYLTAVVKEVLRLHPP 394

  Fly   432 VP------LGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQ 490
            .|      |.|     .:.:|....:..|:..:.:.||:..||..:.:|.||:||||:..:|..:
plant   395 GPLLSWARLAI-----TDTIVDGRLVPAGTTAMVNMWAVSHDPHVWVDPLEFKPERFVAKEGEVE 454

  Fly   491 -----APPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSGTEVDMAGESGIT---LT 547
                 :..:..||.||.|:|||:.:....:..:|..:|..|......|..||::.:..::   ..
plant   455 FSVLGSDLRLAPFGSGRRICPGKNLGFTTVMFWTAMMLHEFEWGPSDGNGVDLSEKLRLSCEMAN 519

  Fly   548 PTPHMLR 554
            |.|..||
plant   520 PLPAKLR 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	110/527 (21%)
CYP78A6	NP_182189.1	p450	25..523	CDD:386267	107/522 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000