DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP705A9

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_180269.1	Gene:	CYP705A9 / 817243	AraportID:	AT2G27010	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	131/563 - (23%)
Similarity:	227/563 - (40%)	Gaps:	120/563 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LVLVILYLCERQCNDLMGAP-------PPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFEL 86
            |:|::|.|....|.......       ||.|..||.:|:|..|.:...|:|||||:.:||.:..|
plant     9 LILILLCLLSFLCYSFFFKKPKDGFNLPPSPPSLPIIGHLHHLLSLFMHRSLQKLSSKYGPLLYL 73

  Fly    87 KMGRVPTVVLSDAALVRDFFR--------RDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRE 143
            .:..||.:::|..::..:.||        ||..|....|     :.|.||...|.....:|:|
plant    74 HVFNVPILLVSSPSIAYEIFRTQDVNVSSRDFPTNEGSL-----LFGSFGFGTAPSSGLKHSR-- 131

  Fly   144 TIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDL 208
                          |..::.........:|:.|:....|..:.....||          |.:..:
plant   132 --------------GHKKSVQRSYYLNLLDKAVKKESVEIAEEAMKLVN----------NTVCQM 172

  Fly   209 VFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDR 273
            :.|             :...||..:...|.|:|                       .||.|:..:
plant   173 IMG-------------RSCSEENGEAERVRGLV-----------------------TKTDALTKK 201

  Fly   274 IVEACGQRLKEKQKV-----FKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEED 333
            .:.| |...|..||:     .|||.:......::.::.|.:.||        :.:|..:.:|
plant   202 FILA-GILRKPLQKIGISLFKKELMDASCKFNEVLEKILVEYKE--------KVEEHHQGTD--- 254

  Fly   334 TYEPECILEHFLAVRDTDSQLY--CDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRL 396
                  :::..|.|...:...|  ..|.::.|..|||.||.||....::|.:..:........||
plant   255 ------MMDKLLEVYGDEKAEYKITRDHIKSLFVDLFFAGTDTWTHAIQWIMAEIINNSYILERL 313

  Fly   397 HELL-LPLGPSPTLEE--LEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIV 458
            .|.: ..:|.:..::|  |..|..|:|.:.|.:|:...||| :....||...:|.:::...:.:|
plant   314 REEIDSVVGKTRLIQETDLPNLPCLQATVKEGLRLHPPVPL-VLRTFKEGCTIGGFYVPEKTTLV 377

  Fly   459 CSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPP------QFIPFSSGYRMCPGEEMARMILTL 517
            .:.:|:..||..:.:|:||:|||||.:..:.|...      :::||.:|.|.|||..:|.:.:..
plant   378 VNGYAMMRDPEYWEDPQEFKPERFLASSRSSQNDEIRDELLKYLPFGNGRRACPGANLAYISVGT 442

  Fly   518 FTGRILRRFHLELPSGTEVDMAGESG-ITLTPTPHMLRFTKLP 559
            ..|.:::.|..|: .|.:::|....| |||| ..|.|..|.:|
plant   443 AIGVMVQCFDWEI-KGDKINMDEAPGKITLT-MAHPLNCTLVP 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	124/530 (23%)
CYP705A9	NP_180269.1	p450	46..486	CDD:299894	121/526 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000