DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and AT2G12190

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_178922.1	Gene:	AT2G12190 / 815688	AraportID:	AT2G12190	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	568	Identity:	143/568 - (25%)
Similarity:	238/568 - (41%)	Gaps:	105/568 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LLVPGALVL-VILYLCERQCNDLMGAP-PPGPWGLPFLGYLPFL--DARAPHKSLQKLAKRYGGI 83
            ||:.|:|.| ::|.|...:..|....| ||.|...||||.|.:|  .....:..|:.:..|.|.|
plant     5 LLILGSLFLSLLLNLLLFRRRDSSSLPLPPDPNFFPFLGTLQWLRQGLGGLNNYLRSVHHRLGPI 69

  Fly    84 FELKMGRVPTVVLSDAALVRDFFRRDVMTG--------RAPLYL-----THGIMGG-FGIICAQE 134
            ..|::...|.:.::|.:|.....   |:.|        .||:..     .|.|... :|.
plant    70 ITLRITSRPAIFVADRSLAHQAL---VLNGAVFADRPPAAPISKIISSNQHNISSSLYGA----- 126

  Fly   135 DIWRHARRE-TIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALH 198
             .||..||. |.:.|       .|..:|:....|  |.|.|.  |||...|......:..:..||
plant   127 -TWRLLRRNLTSEIL-------HPSRVRSYSHAR--RWVLEI--LFDRFGKSRGEEPIVVVDHLH 179

  Fly   199 HSLGNIINDLVFGITYKRDDPDWL---YLQRLQEEGVKLIGVS--GVVNFLPWLRHLPANVRNIR 258
            :::..::..:.||  .|.|:....   |:||.|     |:|.|  .::|..|            :
plant   180 YAMFALLVLMCFG--DKLDEKQIKQVEYVQRRQ-----LLGFSRFNILNLWP------------K 225

  Fly   259 FLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEAD 323
            |       |..|..:..|...|..:|:..|...|   .|.:|::.:|:..:|         ||.:
plant   226 F-------TKLILRKRWEEFFQMRREQHDVLLPL---IRARRKIVEERKNRS---------SEEE 271

  Fly   324 EDDEESDEE--DTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYL 386
            ||::...:.  ||     :||  |.:.|...:|. :|::..|.::....|.||:...|:|.:..|
plant   272 EDNKVYVQSYVDT-----LLE--LELPDEKRKLN-EDEIVSLCSEFLNGGTDTTATALQWIMANL 328

  Fly   387 AREQRCQRRLHELLLPL----GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVG 447
            .:....|:||:|.:..:    ......|:.:.:.||:|.:.|.:|........:||...|:.|:|
plant   329 VKNPEIQKRLYEEIKSVVGEEAKEVEEEDAQKMPYLKAVVMEGLRRHPPGHFVLPHSVTEDTVLG 393

  Fly   448 DYFI--KGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPP----QFIPFSSGYRMCP 506
            .|.:  ||....:.:|  |..||:.:.||..|:||||:..:.|.....    :.:||.:|.|:||
plant   394 GYKVPKKGTINFMVAE--IGRDPMVWEEPMAFKPERFMGEEEAVDITGSRGIKMMPFGAGRRICP 456

  Fly   507 GEEMARMILTLFTGRILRRFHLELPSGTEVDMAGESGITLTPTPHMLR 554
            |..:|.:.|..:...::|.|..:...|.|||:..:...|:. ..|.|:
plant   457 GIGLAMLHLEYYVANMVREFEWKEVQGHEVDLTEKFEFTVV-MKHSLK 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	134/540 (25%)
AT2G12190	NP_178922.1	PLN00168	23..512	CDD:215086	136/550 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000