DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phm and CYP71B9

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_178362.1	Gene:	CYP71B9 / 814788	AraportID:	AT2G02580	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	138/563 - (24%)
Similarity:	221/563 - (39%)	Gaps:	132/563 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LVILYLC----------ERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFE 85
            |.:|:||          :|:.|.   ..||.|.|.|.:|.|..| ...||:||..|:|.||.:..
plant     7 LSLLFLCCILLAAFKHKKRRTNQ---QQPPSPPGFPIIGNLHQL-GELPHQSLWSLSKTYGPVML 67

  Fly    86 LKMGRVPTVVLSDAALVRDFFR--------RDVMTGRAPL---YLTHGIMGGFGIICAQEDIWRH 139
            ||:|.|||||:|.:...:...:        |..:.|...|   ||...       ....:|.|:.
plant    68 LKLGSVPTVVVSSSETAKQVLKINDLHCCSRPSLAGAKELSYNYLDIA-------FSPFDDYWKE 125

  Fly   140 ARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNI 204
            .||..:..|           ..|:....|....:|.||.....|.:| ||:.:|:     :|...
plant   126 LRRICVQEL-----------FSAKRVHSIQPIKEEEVRKLIVSATES-ASQKSPV-----NLSEK 173

  Fly   205 INDLVFGITYKRDDPDWLYLQRLQEEGV-KLI-------GVSGVVNFLP-------WLRHLPANV 254
            ..||...:..|.......:...|..:|. |||       |.....||.|       ||..|
plant   174 FLDLTVSVICKAAFSLDFHTSVLNNDGFDKLIHDAFLFLGSFSASNFFPNGGWIIDWLTGL---- 234

  Fly   255 RNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQ 319
                                     ||.:||.  .|:|....:....|.|::.:|..|
plant   235 -------------------------QRRREKS--VKDLDVFYQQMFDLHKQENKQGVE------- 265

  Fly   320 SEADEDD--EESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWF 382
               |..|  .:.::|:|     :|.:....|         :.::.:|.::....::||..|:.|.
plant   266 ---DFVDLLLKLEKEET-----VLGYGKLTR---------NHVKAILMNVLLGAINTSAMTMTWA 313

  Fly   383 LLYLAREQRCQRRLHELL--LPLGPSP-TLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENF 444
            :..|.|..|..:::...:  ..:..|. ||::::.|.||:..|.||.|:...|||.:|......|
plant   314 MAELIRNPRVMKKVQSEIRNQMINKSVITLDDIDHLPYLKMVIKETWRLHPPVPLLLPREVMSEF 378

  Fly   445 VVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQ---FIPFSSGYRMCP 506
            .:..|.|:..:::..:.|||..||.::.:.:.|.||||:  |....|..|   .:||.||.|:||
plant   379 EINGYKIQPKTLLYVNVWAIGRDPDSWKDADMFYPERFM--DNNIDAKGQNFELLPFGSGRRICP 441

  Fly   507 GEEMARMILTLFTGRILRRFHLELPSG---TEVDMAGESGITL 546
            |..|...::......:|.:|..|:|.|   .::||....|:.:
plant   442 GMYMGTTMVEFGLANMLYQFDWEVPDGMVVEDIDMEESPGLAV 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	132/535 (25%)
CYP71B9	NP_178362.1	p450	7..498	CDD:299894	138/563 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1305
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1659
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050