Protein Alignment phtm and cyp2aa2

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001070926.1
• Gene: cyp2aa2 / 768294
• ZFINID: ZDB-GENE-061027-232
• Length: 498
• Species: Danio rerio
• Alignment Length: 566
• Identity: 151/566 - (26%)
• Similarity: 251/566 - (44%)
• Gaps: 101/566 - (17%)

  Fly     1 MSADIVDIGHTGWMPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLD 65
            :..|:..:|          |::.|   .|:.::|:...| .|...|..||||..|||:|.||.|
Zfish     6 LKLDLATVG----------LTLFL---GLIFLVLFEIFR-INSYKGRFPPGPTPLPFVGNLPHL- 55

  Fly    66 ARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGIMGGFGII 130
            .:.| ...::....|||:..:.:||.|.:.::...|.::...:||.:||.||.:...|..|.|||
Zfish    56 LKNP-MGFKRSLSEYGGLATVFIGRQPAISINTIQLAKEALVQDVFSGRPPLPIFDWISHGLGII 119

  Fly   131 CAQ-EDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPL 194
            ... ...||..||..:..|:..|:.::..|.|.         ::|...|. .|..|.....:||.
Zfish   120 MVTFNHSWRQQRRFALHTLRNFGLGKKTVEDRV---------LEESQYLI-AEMLKDEGKSMNPQ 174

  Fly   195 PALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSG--VVNFLPWLRHLPANVRNI 257
            .||.:::.|||..:|||..::.|:..:.||.::..|.:.|.|.:.  :.|.:|:::|.|
Zfish   175 HALQNAVSNIICSIVFGDRFEYDNKRFEYLLKILNENIMLTGSAAGQIFNLVPFIKHFP------ 233

  Fly   258 RFLLEGKAKTHAIYDRIVEACGQRLKEKQK---VFKELQEQKRLQRQLEKEQLRQSKEADPSQEQ 319
                                 |...|.||.   :|..:::        |.::.:|:.:.|..::.
Zfish   234 ---------------------GPHQKVKQNADDLFNFIRD--------EAKEHKQTLDPDSPRDF 269

  Fly   320 SEA---DEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLL---ADLFGAGVDTSLAT 378
            .:|   :.:.::|.:|.|:..|                       ||:   :|||.||.||:..|
Zfish   270 IDAYLLEIEKQKSSKESTFHEE-----------------------HLVVSTSDLFLAGTDTTETT 311

  Fly   379 LRWFLLYLAREQRCQRRLH-ELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGC 440
            :||.|:||.:....|.|.| |::..||..  |::::.:.|.|..|.:.|..|..::.|..:....
Zfish   312 IRWGLIYLIQNPDVQERCHEEIVQVLGYDRLPSMDDRDKLPYTLATVHEIQRCGNIAPKLLHETI 376

  Fly   441 KENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMC 505
            :...:.| |.|..|:.|:.:..|:..|...:..|:.|.||.||..:|.:..|..|.|||.|.|.|
Zfish   377 RRTKLHG-YDIPQGTTIIANFTAMFSDKELWKHPDAFNPENFLDENGQFSKPEYFFPFSLGPRAC 440

  Fly   506 PGEEMARMILTLFTGRILRRFHLELPSGTE-VDMAGESGITLTPTP 550
            .||.:||..|.||...:|:|.....|...: :||.|..||..:|.|
Zfish   441 LGEALARTELFLFITSLLQRIRFSWPPNAKPIDMDGIVGIVRSPEP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	129/486 (27%)
cyp2aa2	NP_001070926.1	cytochrome_P450	69..489	CDD:477761	130/487 (27%)