Protein Alignment phtm and cyp2k17

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001036243.2
• Gene: cyp2k17 / 735313
• ZFINID: ZDB-GENE-070424-41
• Length: 503
• Species: Danio rerio
• Alignment Length: 567
• Identity: 147/567 - (25%)
• Similarity: 255/567 - (44%)
• Gaps: 102/567 - (17%)

  Fly    17 VQSL----SILLVPGALVLVILYL-------CERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPH 70
            |:||    |:..:.|.|:|::::.       .:::..|     ||||..:|.||.|..||...|.
Zfish     3 VESLLHFSSVGTLLGTLLLLLVFYRLSRDSEFQKKRKD-----PPGPKPIPLLGNLLTLDLSRPF 62

  Fly    71 KSLQKLAKRYGGIFELKMGRVPTVVLSDAALVR--------DFFRRDVMTGRAPLYLTHGIMGGF 127
            .||.:|:|.||.::::.:|....|||.....|:        :|..||:    .|::..  :....
Zfish    63 DSLCELSKTYGNVYQVFLGPKKVVVLIGHKTVKEALVNFADEFGERDI----TPIFRI--LANDH 121

  Fly   128 GIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVN 192
            ||:.:..:.|:..||..|..|:..||.:|..|.:...|....:|          |..|......:
Zfish   122 GILFSNGESWKEMRRFAISNLRDFGMGKRGSEEKIIEEIHHLKG----------EFDKFEGKPFD 176

  Fly   193 PLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVV--NFLPWLRHLPANVR 255
            ....:::::.|||:.:|:|..::..||.:..:.....|.:::.|.:.::  |..|||.....:.|
Zfish   177 TTQPVNYAVSNIISSIVYGSRFEYTDPRFTEMVDRANENIRVSGSASMMLYNIFPWLGPFLNSKR 241

  Fly   256 N-IRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQ---LEKEQLRQSKEADPS 316
            . :|.:|:.:|                  |..|:...|||...:..:   ::...:|:
Zfish   242 TVVRNMLKNRA------------------EFMKLITGLQETLNIHDRRGFVDSFLIRK------- 281

  Fly   317 QEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRW 381
                   :.||:..::|||                   :..:.|...:.:||.||.||:..||||
Zfish   282 -------QSDEQLGKKDTY-------------------FHAENLLMTVGNLFAAGTDTTGTTLRW 320

  Fly   382 FLLYLAREQRCQRRLHELLLPL--GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENF 444
            .|:.:|:..:.|.|:.|.:..:  |..|.:|:.:.|.|..|.|.|..|:.::||:.:||....:.
Zfish   321 GLMLMAKYPQIQDRVQEEIDRVIGGRQPVVEDRKKLPYTDAVIHEIQRLANIVPMNLPHVTSCDV 385

  Fly   445 VVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEE 509
            ....||||.|:.::....::..|...:.:|..|.||.||...|.:.....|:|||:|.|:|.||.
Zfish   386 TFNGYFIKKGTTVIPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFIKRDAFMPFSAGRRVCLGES 450

  Fly   510 MARMILTLFTGRILRRFHLELPSGT---EVDMAGESGITLTPTPHML 553
            :|||.|.||...:|:.:....|.|.   |:|:.|..|:||.|:||.|
Zfish   451 LARMELFLFFASLLQSYRFTTPPGVSEDELDLKGTVGVTLNPSPHKL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	122/490 (25%)
cyp2k17	NP_001036243.2	cytochrome_P450	72..497	CDD:477761	123/491 (25%)