Protein Alignment phtm and Cyp2ab1

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_017453675.1
• Gene: Cyp2ab1 / 679979
• RGDID: 1586963
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 129/493 - (26%)
• Similarity: 216/493 - (43%)
• Gaps: 79/493 - (16%)

  Fly    75 KLAKRYGGIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIW 137
            :||:.:|.:|.:.:|..|.|||:....|::..  ..:..:||........:.|..|:||:....|
  Rat    53 QLAQTHGNVFTVWLGSTPIVVLNGFRAVKEALVSNSEQFSGRPLTPFFRDLFGEKGVICSNGLTW 117

  Fly   138 RHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLG 202
            |..||..:..|:.||:.::..||:.:.|      ..|...:|..|..::    .:|...:..|..
  Rat   118 RQQRRFCLTTLRELGLGKQALELQLQHE------AAELAEVFHQEQGRA----FDPQVPIIRSTT 172

  Fly   203 NIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVS--GVVNFLPW-LRHLPANVRNIRFLLEGK 264
            .:|..||||..:..::|.:|.|.|....|:.....:  .:.:..|| ||:|..
  Rat   173 RVIGALVFGHHFLSEEPIFLELIRAINLGLAFASTTWRRLYDMFPWALRYLSG------------ 225

  Fly   265 AKTHAIYDRIVEACGQRLKEKQKVFKELQEQKR--LQRQLEKEQLRQSKEADPSQEQSEADEDDE 327
                               ..||:| :..|..|  :..::.:.:||          ..||.:|
  Rat   226 -------------------PHQKIF-QYHEAVRGFIHHEIIRHKLR----------TPEAPKD-- 258

  Fly   328 ESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYL----AR 388
                    ...|.|.......|.....:.::.|..::.|||..|.||:..||.|.::||    |.
  Rat   259 --------FISCYLSQITKAMDDPVSTFSEENLIQVVIDLFLGGTDTTATTLHWAIIYLVHHRAI 315

  Fly   389 EQRCQRRLHELLLPLGPSPTL--EELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFI 451
            ::|.|:.|.|:   ||.:..:  |:.|.|.|.||.:.|..|:.|||.:|....|.....:..|::
  Rat   316 QERVQQELDEV---LGTAQAVCYEDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTPTWMHGYYV 377

  Fly   452 KGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILT 516
            ..|::|:.:..::..||..:..|.:|.|..||..||.:.....|:|||:|:|:||||::|||.|.
  Rat   378 SKGTIILPNLASVLCDPECWETPHQFNPGHFLDKDGDFVTNEAFLPFSAGHRVCPGEQLARMELF 442

  Fly   517 LFTGRILRRFHLELPSGTE-VDMAGESGITLTPTPHML 553
            |....:||.|..:||.|:: :.:....|.||.|.|..:
  Rat   443 LMFATLLRTFRFQLPEGSQGLRLEYVFGGTLQPQPQKI 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	127/485 (26%)
Cyp2ab1	XP_017453675.1	CYP2AB1-like	58..480	CDD:410760	127/486 (26%)