Protein Alignment phm and Cyp2j8

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001098397.1
• Gene: Cyp2j8 / 665095
• MGIID: 2449817
• Length: 503
• Species: Mus musculus
• Alignment Length: 549
• Identity: 134/549 - (24%)
• Similarity: 247/549 - (44%)
• Gaps: 86/549 - (15%)

  Fly    21 SILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYL-PF-LDARAPHKSLQKLAKRYGGI 83
            ::||....|:|::.|:..|...:.    |||||.|||:|.| .| ||....|..:|...|:||.:
Mouse    20 TLLLAALTLLLLVDYIKNRHPKNY----PPGPWRLPFVGNLFQFDLDVSHLHLGIQPFVKKYGNL 80

  Fly    84 FELKMGRVPTVVLSDAALVRD--------FFRRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHA 140
            ..|..|.:|:|::|...|:::        |.:|.::..|..::..:||:...|      ..|:..
Mouse    81 ISLDFGTIPSVIISGEPLIKEALTCMGQNFLKRPILAARQHIFKNNGIISSSG------QTWKEQ 139

  Fly   141 RRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNII 205
            ||.|:..||..|:.::      .||:||.   ||...|.:..|::. ....:|...:::::.|||
Mouse   140 RRFTLMILKNFGLGKK------SLEQRIQ---DEAHHLVEAIAEEK-GRPFDPHFMINNAVSNII 194

  Fly   206 NDLVFGITYKRDDPDWLYLQRLQEEGVKLIG--VSGVVNFLPWL-RHLPANVRNIRFLLEGKAKT 267
            ..:..|..::.:|..:..|.:|.:|.:.|..  |..:.|..|.: ::||.
Mouse   195 CSITIGERFEYEDNQFQELLKLADETLCLEASKVLMLYNVFPSIFKYLPG--------------- 244

  Fly   268 HAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEE 332
                            ..||:|...::.|.....:...   ..|:.:||..:...|
Mouse   245 ----------------PHQKLFSNWEKLKLFFSHVMDS---HRKDWNPSAPRDFID--------- 281

  Fly   333 DTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLH 397
                  ..|.......|..:..:.::.|.....|||.||.:|:...|||.|||:......|.::|
Mouse   282 ------AFLTEMAKYSDKTTTSFNEENLICTTLDLFFAGTETTSTALRWALLYITVNPEVQEKVH 340

  Fly   398 ---ELLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVC 459
               :.::..|..||:::.:.:.|..|.|.|.:|:.:::||.:|...:.:..:..:.:..|:|::.
Mouse   341 SEIDRVIGQGRHPTIDDRDSMPYTNAVIHEVLRMGNIIPLNVPREVEADITLAGFHLPKGTMVLT 405

  Fly   460 SEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILR 524
            :..|:|.||..:..|:.|.||.|| .:|.::....|:|||.|.|.||||::||..|..|...:::
Mouse   406 NLTALHRDPKEWATPDVFNPEHFL-ENGQFKKRESFLPFSVGKRGCPGEQLARSELFTFFTALMQ 469

  Fly   525 RFHLELPSGTEVDMAGESGITLTPTPHML 553
            :|..:.|...::.:..:.|:.|:|..:.:
Mouse   470 KFTFKPPINEKLSLNFKMGVALSPVSYCI 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	128/521 (25%)
Cyp2j8	NP_001098397.1	p450	44..499	CDD:365848	128/521 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910