Protein Alignment phtm and cyp2aa1

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001020728.2
• Gene: cyp2aa1 / 572000
• ZFINID: ZDB-GENE-070424-33
• Length: 498
• Species: Danio rerio
• Alignment Length: 543
• Identity: 145/543 - (26%)
• Similarity: 244/543 - (44%)
• Gaps: 83/543 - (15%)

  Fly    19 SLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLP-FLDARAPHKSLQKLAKRYGG 82
            |:.:.|..|.:.||:..:.  :.:...|..||||..|||:|.|| ||  ::|.:.: :...:||.
Zfish    12 SVGLTLFLGLIFLVLFEIF--RIHSYKGRFPPGPTPLPFVGNLPHFL--KSPMEFI-RFMPQYGE 71

  Fly    83 IFELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGIMGGFGIICAQ-EDIWRHARRETID 146
            :..:..||.|.::|:...|.::.:.:||.:||..:.|...|..|.||:... .:.||..||..:.
Zfish    72 MTTIFFGRKPVIMLNTIQLAKEAYVQDVFSGRPAIPLFDWITNGLGIVMVTFNNSWRQQRRFALH 136

  Fly   147 WLKALGMTRRPGELRARLERR--IARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLV 209
            .|:..|:.::..|.|...|.|  ||            |..|.....:||..||.:::.|||..:|
Zfish   137 TLRNFGLGKKTVEDRVLEESRYLIA------------EMLKEEGKSMNPQHALQNAISNIICSIV 189

  Fly   210 FGITYKRDDPDWLYLQRLQEEGVKLIGVSG--VVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYD 272
            ||..::.|:..:.||.:...|.:.|.|.:.  :.|.:|:::|.|.
Zfish   190 FGDRFEYDNKRFEYLLKTLNENIMLAGSAAGQIFNLVPFIKHFPG-------------------- 234

  Fly   273 RIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEA---DEDDEESDEEDT 334
                       ..||:.:...|.....|...||. ||:.:.|..::..:|   :.:.::|.::.|
Zfish   235 -----------PHQKIKQNADELLGFIRDEAKEH-RQTLDPDSPRDFIDAYLLEIEKQKSSKDST 287

  Fly   335 YEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLH-E 398
            :..|.::..                    .:|||.||.||:..|:||.|:.|.:....|.|.| |
Zfish   288 FHEENLVVS--------------------ASDLFLAGTDTTETTIRWGLINLIQNPDVQERCHEE 332

  Fly   399 LLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSE 461
            ::..||..  |::::.:.|.|..|.:.|..|..::.| .:.|.......:..|.|..|::|:.:.
Zfish   333 IVRVLGYDRLPSMDDRDKLPYTLATVYEIQRCANIAP-NVMHQTILPTKLHGYNIPQGTIILTNL 396

  Fly   462 WAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRF 526
            .||..:...:..|:.|.||.||..:|.:..|..|||||.|.|:|.||.:||..|.||...:|:|.
Zfish   397 AAIFSNKEHWKHPDAFNPENFLDENGHFSKPESFIPFSLGPRVCLGETLARTELFLFITALLQRI 461

  Fly   527 HLELPSGTE-VDMAGESGITLTP 548
            ....|...: :||.|..|:..:|
Zfish   462 RFSWPPDAKPIDMDGIMGLVRSP 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	125/480 (26%)
cyp2aa1	NP_001020728.2	cytochrome_P450	69..489	CDD:477761	126/481 (26%)