Protein Alignment phtm and cyp2r1

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001373291.1
• Gene: cyp2r1 / 563369
• ZFINID: ZDB-GENE-110114-1
• Length: 506
• Species: Danio rerio
• Alignment Length: 552
• Identity: 144/552 - (26%)
• Similarity: 251/552 - (45%)
• Gaps: 78/552 - (14%)

  Fly    13 WMPSVQSLSILLVPGALVLVILYLCERQCNDLMGAP---PPGPWGLPFLGYLPFLDARAPHKSLQ 74
            |..::..|..|.....::|||..|.:::      .|   ||||..||.:|.:..| |..||..::
Zfish    15 WEQTLICLLGLFTTLLILLVIRQLVKQR------RPRGFPPGPTPLPIIGNMLSL-ATEPHVYMK 72

  Fly    75 KLAKRYGGIFELKMGRVPTVVLSDAALVRD--FFRRDVMTGR--APLYLTHGIMGGFGIICAQED 135
            :.:..:|.||.|.:|.:|||:|:....:::  :.:.:|...|  .||:.....|||. :.|....
Zfish    73 RQSDIHGQIFSLDLGGIPTVILNGYDAIKECLYHQSEVFADRPSLPLFQKMTKMGGL-LNCKYGR 136

  Fly   136 IWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHS 200
            .|....:..::..:..|..:|..|       ||:   :||:...|. ..:......||...:.::
Zfish   137 GWIEHHKLAVNCFRYFGTGQRMFE-------RIS---EECLYFLDA-IDQHQGKPFNPKHLVTNA 190

  Fly   201 LGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSG--VVNFLPWLRHLPANVRNIRFLLEG 263
            :.||.|.::||..:..||.|:.::..:..|.|:|...|.  :.|..||:.:||.          |
Zfish   191 VSNITNLIIFGQRFTYDDGDFQHMIEIFSENVELAASSWAFLYNAFPWMEYLPF----------G 245

  Fly   264 KAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEE 328
            |                    .|::|:...|..:...|:.: :..|.:.....|...:|..|:.|
Zfish   246 K--------------------HQRLFRNANEVYKFLLQIIR-RFSQGRVPQSPQHYIDAYLDEME 289

  Fly   329 SDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQ 393
            ....|                 .:..:..|.|...:.:|..||.:|:...|||.:||:|...|.|
Zfish   290 QSTPD-----------------KATSFSQDNLIFSVGELIIAGTETTTNCLRWAMLYMALYPRIQ 337

  Fly   394 RRLH-ELLLPL-GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSM 456
            .::. |:...| |..|..|:.:.:.|:.|.:.|.:|:.::|||||.....::.||..|.|..|:|
Zfish   338 EKVQMEIDSVLNGRQPAFEDRQRMPYVEAVLHEVLRLCNIVPLGIFRATSQDAVVRGYTIPKGTM 402

  Fly   457 IVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGR 521
            ::.:.:::|.|...:.:|..|.|||||..:|.:.....|:|||.|.|.|.||::||:.:.||...
Zfish   403 VITNLYSVHFDEKYWSDPSIFCPERFLDCNGKFIRHEAFLPFSIGKRHCLGEQLARLEMFLFFTT 467

  Fly   522 ILRRFHLELPSGTEVDMAGESGITLTPTPHML 553
            :|:||||:...|....::.:.|:||.|.|:.:
Zfish   468 LLQRFHLQFSEGFIPSLSAKLGMTLQPQPYSI 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	125/479 (26%)
cyp2r1	NP_001373291.1	CYP2R1	67..500	CDD:410754	127/493 (26%)