Protein Alignment phtm and cyp2k19

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001073172.1
• Gene: cyp2k19 / 562304
• ZFINID: ZDB-GENE-091211-1
• Length: 502
• Species: Danio rerio
• Alignment Length: 554
• Identity: 148/554 - (26%)
• Similarity: 241/554 - (43%)
• Gaps: 97/554 - (17%)

  Fly    24 LVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELKM 88
            |:...|:.::|||.. ..:...|..||||..||.||.|..||......:..:|:|.||.:|::.:
Zfish    16 LLAALLLFLVLYLVS-SGSQKEGKEPPGPKPLPLLGNLLTLDLTRAFDTFFELSKTYGNVFQVFL 79

  Fly    89 GRVPTVVLSDAALVRD--------FFRRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETI 145
            |...||||.....|::        |..|::..|...:...|||:...|      :.|:..||..:
Zfish    80 GPRKTVVLVGYKTVKEALVNYAEQFGDREIGPGFRIMNDEHGILFSNG------ENWKEMRRFAL 138

  Fly   146 DWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVF 210
            ..|:..||.:|..|.:...|....:|          |..|......:....:::::.|||:.:|:
Zfish   139 SNLRDFGMGKRGSEEKIIEEIHHLKG----------EFDKFEGKPFDTTQPVNYAVSNIISSIVY 193

  Fly   211 GITYKRDDPDWLYLQRLQEEGVKLIGVSGVVN-----FLPWLRHLPANVRNIRFLLEGKAKTHAI 270
            |..::..||.:..:.....|.|:   |.|.|:     ..||:
Zfish   194 GSRFEYTDPQFTEMVDRANENVR---VGGSVSMWFHEMFPWV----------------------- 232

  Fly   271 YDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADE------DDEES 329
                    |..||.|:.:.:.:.:.:   .|:.|......:..:|:..:...|.      .||:|
Zfish   233 --------GPFLKSKRIIVENIIQSR---AQMTKLITALLETLNPNDPRGFVDSFLTRKLSDEKS 286

  Fly   330 DEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQR 394
            .::|:|                   :.::.|...:.:||.||.||:..||||.|:.:|:..:.|.
Zfish   287 GKKDSY-------------------FHEENLIMTVTNLFVAGTDTTGTTLRWGLMLMAKYPQIQD 332

  Fly   395 RLHELLLPL--GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMI 457
            |:.|.:..:  |..|.:|:.:.|.|..|.|.|..|:.::|||.:||....:.....||||.|:.:
Zfish   333 RVQEEIDRVIGGRQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHKTTSDITFNGYFIKKGTTV 397

  Fly   458 VCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRI 522
            |....::..|...:.:|..|.||.||...|.:.....|||||:|.|:|.||.:|||.|.||...:
Zfish   398 VPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFIPFSAGRRVCLGESLARMELFLFFTSL 462

  Fly   523 LRRFHLELPSGT---EVDMAGESGITLTPTPHML 553
            |:.:....|.|.   |:|:.|..||||.|:||.|
Zfish   463 LQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	127/495 (26%)
cyp2k19	NP_001073172.1	cytochrome_P450	71..496	CDD:477761	128/496 (26%)