Protein Alignment phtm and cyp2k8

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001124095.1
• Gene: cyp2k8 / 561462
• ZFINID: ZDB-GENE-080721-19
• Length: 507
• Species: Danio rerio
• Alignment Length: 566
• Identity: 156/566 - (27%)
• Similarity: 259/566 - (45%)
• Gaps: 112/566 - (19%)

  Fly    19 SLSILLVPGALVLVILYLCERQCNDLMGAP--PPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYG 81
            |::.:|:...|:.:::||.....:    :|  ||||..||.||.|..||.:..|.||.:|:|:||
Zfish    12 SITGVLLSAVLLFLVVYLISISSS----SPEDPPGPKPLPLLGNLHTLDLKNLHVSLWELSKKYG 72

  Fly    82 GIFELKMGRVPTVVLSDAALVR--------DFFRRDVMTGRAPLYLTHGIMGGFGIICAQEDIWR 138
            .:|::.:||...|||:....|:        :|..||:    .|::  .....|.||:.|..:.||
Zfish    73 PVFKVHLGRKKVVVLAGYKTVKQALVNQAEEFGERDI----TPIF--QDCNQGQGIVFANGERWR 131

  Fly   139 HARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRL----FDTEAKKSCASEVNPLPALHH 199
            ..||..:..|:..||.::..|.:...|.|..|.|  .::.    |||         ..|   :::
Zfish   132 TMRRFALSTLRDFGMGKKLSEEKIVDETRYLREV--FMKFEGQPFDT---------TQP---VNY 182

  Fly   200 SLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIG--VSGVVNFLPWLRHLPANVRNIRFLLE 262
            ::.|||:.:|:|..::.:||.:..:.......:::||  |..:.|..|:|
Zfish   183 AVSNIISAIVYGKRFEYEDPAFQDMVNKANMNIRMIGSAVIQIYNMCPFL--------------- 232

  Fly   263 GKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDE 327
                            |..:|..:::.|.::..:|..:.|          ||..||
Zfish   233 ----------------GPWIKTWRQLMKNMESTRRQIQTL----------ADVLQE--------- 262

  Fly   328 ESDEEDTYEP-EC--ILEHFLA----VRDT---DSQLYCDDQLRHLLADLFGAGVDTSLATLRWF 382
                  |..| :|  :::.||.    :::|   ||. :.|..|...:::||.||.||:..||||.
Zfish   263 ------TLNPLDCRGLIDSFLIRKQNIQETGEKDSS-FNDQNLLITVSNLFAAGTDTTGTTLRWG 320

  Fly   383 LLYLAREQRCQRRLHELLLPL--GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFV 445
            |:.:|:..:.|.|:.|.:..:  |..|..|:.:.|.|..|.|.||.|:.:::||.:||....:..
Zfish   321 LMLMAKYPQIQDRVQEEIDQVLGGREPVAEDRKNLPYTDAVIHETQRLANILPLNLPHKTSCDVT 385

  Fly   446 VGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEM 510
            ...||||.|:.::....::..|...:..|:.|.|:.||...|.......|:|||:|.|.|.||.:
Zfish   386 FNGYFIKKGTCVLPLLTSVLRDETEWETPDTFNPQHFLDEKGQLIKRDAFMPFSAGRRACLGESL 450

  Fly   511 ARMILTLFTGRILRRFHLELPSGT---EVDMAGESGITLTPTPHML 553
            |||.|.||...:|:.|....|.|.   |:|:....|:||.|:||.|
Zfish   451 ARMELFLFFTSLLQYFRFSPPPGASEDELDLTPVVGLTLNPSPHKL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	132/500 (26%)
cyp2k8	NP_001124095.1	cytochrome_P450	71..496	CDD:477761	133/501 (27%)