Protein Alignment phtm and Cyp2c67

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001019890.1
• Gene: Cyp2c67 / 545288
• MGIID: 3612288
• Length: 491
• Species: Mus musculus
• Alignment Length: 551
• Identity: 139/551 - (25%)
• Similarity: 223/551 - (40%)
• Gaps: 98/551 - (17%)

  Fly    32 VILYLC---------ERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELK 87
            |:|.||         .|| ....|..||||..||.:|....:|.:...:.|...:|.||.:|.|.
Mouse     5 VVLVLCLSFLLVLSLWRQ-RSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLY 68

  Fly    88 MGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKA 150
            .|..|.|||.....:::.|  ..:..:||........:..|.||..:..::|:..|..||:.|:.
Mouse    69 FGSQPIVVLHGYEAMKEAFIDHGEEFSGRGRFPFFDKVTKGKGIGFSHGNVWKATRVFTINTLRN 133

  Fly   151 LGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYK 215
            |||.:          |.|...|.|..:....|.||:.....:|...:..:..|:|..:||...:.
Mouse   134 LGMGK----------RTIENKVQEEAQWLMKELKKTNGLPCDPQFIIGCAPCNVICSIVFQNRFD 188

  Fly   216 RDDPDWLYLQRLQEEGVKLIGVSG--VVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEAC 278
            ..|.|:|.|.....|..:::...|  :.|.:|.|                           ::.|
Mouse   189 YKDKDFLSLIGKVNECTEILSSPGCQIFNAVPIL---------------------------IDYC 226

  Fly   279 GQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEH 343
            ..|   ..|.||.       ...::...|.:.||.:.|.               |...|...:::
Mouse   227 PGR---HNKFFKN-------HTWIKSYLLEKIKEHEESL---------------DVTNPRDFIDY 266

  Fly   344 FLAVRDTDSQL----YCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELL---L 401
            ||..|..:..:    |..:.|..|:.||...|.::..:|:|:.||.|.:......::.|.:   :
Mouse   267 FLIQRCQEKGIEHMEYTIEHLATLVTDLVFGGTESLSSTMRFALLLLMKHTHITAKVQEEIDNVI 331

  Fly   402 PLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPH--GCKENFVVGDYFIKGGSMIVCSEWAI 464
            ....||.:::...:.|..|.:.|..|...:.|:.:.|  .|...|  .:|||..|:.::.|..::
Mouse   332 GRHRSPCMQDRNHMPYTNAMVHEVQRYVDLGPISLVHEVTCDTKF--RNYFIPKGTQVMTSLTSV 394

  Fly   465 HMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLE 529
            ..|...||.||.|.|..||..:|.::....|:|||:|.|:|.||.:|||.|.||...||:.|.|:
Mouse   395 LHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLK 459

  Fly   530 -LPSGTEVDMAGESGITLTPTPHMLRFTKLP 559
             |....::||          ||....|:|:|
Mouse   460 PLVDPKDIDM----------TPKHSGFSKIP 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	118/485 (24%)
Cyp2c67	NP_001019890.1	CYP2C-like	61..485	CDD:410758	122/494 (25%)