Protein Alignment phm and Cyp2d11

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001098001.1
• Gene: Cyp2d11 / 545123
• MGIID: 88603
• Length: 504
• Species: Mus musculus
• Alignment Length: 528
• Identity: 138/528 - (26%)
• Similarity: 227/528 - (42%)
• Gaps: 92/528 - (17%)

  Fly    49 PPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFFRRDVMT- 112
            ||||...|.||.|..:|......||.||..|||.:|.|:||..|.||::....:::.    ::|
Mouse    37 PPGPVPWPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEV----LLTC 97

  Fly   113 -------GRAPLYLTHGIM-GGFGIICA-QEDIWRHARRETIDWLKALGMTRRPGELRARLERRI 168
                   .:.|::...|:. |..|::.| ....|:..||.::..|:..|:.::      .||..:
Mouse    98 GEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWQEQRRFSVSTLRNFGLGKK------SLEDWV 156

  Fly   169 ARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQR----LQE 229
            .:........|..:|.:|    :||...|::::.|:|..|:|...::.:||   ||.|    |:|
Mouse   157 TKEARHLCDAFTAQAGQS----INPNTMLNNAVCNVIASLIFARRFEYEDP---YLIRMLKMLKE 214

  Fly   230 EGVKLIG-VSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQ 293
            ...::.| :.||:|..|....:|...   ..:.:|:....||.|.:       |.|.:..:
Mouse   215 CFTEISGFIPGVLNEFPIFLRIPGLA---DMVFQGQKSFMAILDNL-------LTENRTTW---- 265

  Fly   294 EQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLA----VRDTDSQL 354
                                ||.|                  .|..:.:.|||    .:......
Mouse   266 --------------------DPDQ------------------PPRNLTDAFLAEIEKAKGNPESS 292

  Fly   355 YCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRL-HELLLPLG--PSPTLEELEPLA 416
            :.|:.||.::.|||.||:.|:..||.|.||.:......|||: .|:...:|  ..|.:.:...:.
Mouse   293 FNDENLRMVVGDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVQHPEMADQARMP 357

  Fly   417 YLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPER 481
            |..|.|.|..|...:.||.:|.....:..|.|:.:..||.::.:..::..|...:.:|..|.||.
Mouse   358 YTNAVIHEVQRFGDIAPLPLPRITSRDIEVQDFLVTKGSTLIPNMSSVLKDETVWEKPLRFHPEH 422

  Fly   482 FLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSG-TEVDMAGESGIT 545
            ||.|.|.:..|..|:|||:|:|.|.||.:|||.|.||...:|:||.:.:|.| .:........|.
Mouse   423 FLDAQGHFVKPEAFMPFSAGHRSCLGEALARMELFLFFTCLLQRFSISVPDGQPQPSNYRVHAIP 487

  Fly   546 LTPTPHML 553
            :.|.|:.|
Mouse   488 VAPFPYQL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	138/528 (26%)
Cyp2d11	NP_001098001.1	p450	37..496	CDD:278495	138/528 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000