Protein Alignment phtm and Cyp2f4

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_062176.1
• Gene: Cyp2f4 / 54246
• RGDID: 2476
• Length: 491
• Species: Rattus norvegicus
• Alignment Length: 553
• Identity: 150/553 - (27%)
• Similarity: 234/553 - (42%)
• Gaps: 89/553 - (16%)

  Fly    19 SLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGI 83
            |.:|||    |:|.::.|.....:...|..||||..||.||.|..|.::....||.||:|.||.:
  Rat     5 STAILL----LLLAVISLSLTFTSWGKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSKDYGSV 65

  Fly    84 FELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETID 146
            |.:.:|....:|||....|::..  :.:..:||....:......|.||..:..:.|:..||.::.
  Rat    66 FTVYLGPRRVIVLSGYQTVKEALVDKGEEFSGRGSYPIFFNFTKGNGIAFSDGERWKILRRFSVQ 130

  Fly   147 WLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFG 211
            .|:..||.:|      .:|.||   ::|...|.|. .:|:.....:|:..|..|:.|||..::||
  Rat   131 ILRNFGMGKR------SIEERI---LEEGSFLLDV-LRKTEGKPFDPVFILSRSVSNIICSVIFG 185

  Fly   212 ITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNI-RFLLEGKAKTHAIYDRIV 275
            ..:..||...|.:.....:..:::.       .||     ..:.|| ..||:.....|
  Rat   186 SRFDYDDERLLTIIHFINDNFQIMS-------SPW-----GEMYNIFPSLLDWVPGPH------- 231

  Fly   276 EACGQRLKEKQKVFKELQEQKRL-QRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPEC 339
                      ::||:.....|.| .|.:.:.|                       |..|...|..
  Rat   232 ----------RRVFRNFGGMKDLIARSVREHQ-----------------------DSLDPNSPRD 263

  Fly   340 ILEHFLAVRDTDSQLYCDDQLRHLLAD---------LFGAGVDTSLATLRWFLLYLAREQRCQRR 395
            .::.||.....:.|    |.|.|...|         ||| |.:|...|||...|.|.:..:.|.|
  Rat   264 FIDCFLTKMVQEKQ----DPLSHFNMDTLLMTTHNLLFG-GTETVGTTLRHAFLILMKYPKVQAR 323

  Fly   396 LHELL-LPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMI 457
            :.|.: ..:|.|  ||||:...:.|..|.|.|..|...|:|:.:||....:.....:.|..|:.:
  Rat   324 VQEEIDCVVGRSRMPTLEDRASMPYTDAVIHEVQRFADVIPMNLPHRVIRDTPFRGFLIPKGTDV 388

  Fly   458 VCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRI 522
            :.....:|.|...|..|:||.||.||.|:.:::..|.|:|||:|.|:|.||.:|||.|.::...|
  Rat   389 ITLLNTVHYDSDQFKTPQEFNPEHFLDANQSFKKSPAFMPFSAGRRLCLGEPLARMELFIYLTSI 453

  Fly   523 LRRFHLE-LPSGTEVDMAG-ESGITLTPTPHML 553
            |:.|.|. |....::|:.. .||:...|.|..|
  Rat   454 LQNFTLHPLVEPEDIDLTPLSSGLGNLPRPFQL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	125/489 (26%)
Cyp2f4	NP_062176.1	Cyp2F	62..486	CDD:410762	126/490 (26%)