Protein Alignment phtm and cyp2x6

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001013583.1
• Gene: cyp2x6 / 541440
• ZFINID: ZDB-GENE-050320-144
• Length: 491
• Species: Danio rerio
• Alignment Length: 561
• Identity: 142/561 - (25%)
• Similarity: 235/561 - (41%)
• Gaps: 94/561 - (16%)

  Fly    21 SILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFE 85
            |:|:|...|::..|...::..|.     ||||..:|..|.|..|:...|.|..:|.|::||.||.
Zfish     5 SLLVVICILLIFFLIRVKKPKNF-----PPGPPPVPIFGSLLQLNLANPLKDFEKFAEKYGEIFS 64

  Fly    86 LKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQ-EDIWRHARRETIDW 147
            |..|..|.|:|:..|::::..  :....:||...::........||:.|. ..:.:..||..:..
Zfish    65 LYTGSRPAVILNSFAVIKEALVTKAQDFSGRPQDFMISHATENKGIVLADYGPVLKGHRRFALMT 129

  Fly   148 LKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGI 212
            ::..|:.::      .:|.||...:...|...|    |:....|:|....|:...|:|:.|:||.
Zfish   130 MRNFGLGKQ------SMEERILGEISHVVDYLD----KNAGKRVDPHIMFHNVASNVISLLLFGC 184

  Fly   213 TYKRDDPDWL--YLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYD--- 272
            .:..:. ::|  |:|.:.|       :|.::|. ||                     :.|||
Zfish   185 RFDYNS-EFLQCYIQLINE-------ISKIING-PW---------------------NMIYDTFP 219

  Fly   273 --RIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTY 335
              ||:....::..:..||.|.: ..|.:                           ||........
Zfish   220 LLRILPLPFKKAFDHVKVIKSM-NLKLI---------------------------DEHKSTRVPG 256

  Fly   336 EPECILEHFLAVRDTDS---QLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAR----EQRCQ 393
            ||...::.:|...|...   ..:.:|:|...:.||..||.||...||....|||..    :.:||
Zfish   257 EPRDFIDCYLDELDKGKNCVSTFSEDKLLMSIMDLHFAGTDTISNTLLTAFLYLMNHPEVQVKCQ 321

  Fly   394 RRLHELLLPLGPSPTL-EELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMI 457
            :.:.::|  .|....: |:...:.|..|.|.|..|:.:.|||.:.|....:..:..|.|..|::|
Zfish   322 QEIDDVL--EGKDRVMYEDRHNMPYTLAVIHEVQRVANTVPLSVFHSTTRDTELMGYSIPKGTII 384

  Fly   458 VCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRI 522
            :.:...:..:...:..|.||.|..||...|.::.|..|||||:|.|||.||.:|||.|.|....:
Zfish   385 IPNLTRVLKEEGQWKFPYEFNPANFLNEQGQFEKPEAFIPFSTGLRMCLGEGLARMELFLIFVAL 449

  Fly   523 LRRFHLELP-SGTEVDMAGESGITLTPTPHMLRFTKLPAVE 562
            ||||..|.| ...:.|.....|:||||.|:.:...:...|:
Zfish   450 LRRFQFEWPVDAGKPDYTPVFGLTLTPKPYRMHIRRRETVK 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	122/490 (25%)
cyp2x6	NP_001013583.1	CYP2	59..481	CDD:410652	123/491 (25%)