Protein Alignment phtm and Cyp2c24

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001258283.1
• Gene: Cyp2c24 / 499353
• RGDID: 1563697
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 556
• Identity: 142/556 - (25%)
• Similarity: 238/556 - (42%)
• Gaps: 96/556 - (17%)

  Fly    20 LSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            |.::|....|:|:.|:   ||.:. .|..||||..||.:|.:..:|.:...||....:|.||.:|
  Rat     5 LVLVLTLSCLLLLSLW---RQSSG-RGKLPPGPTPLPIIGNILQIDVKDISKSFTNFSKIYGPVF 65

  Fly    85 ELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDW 147
            .|..|..||||:.....|::..  ..:..:||....:...:..|.|:|.:....|:..|..::..
  Rat    66 TLYFGPKPTVVVHGYEAVKEALDDLGEEFSGRGSFPIVERMNNGLGVIFSNGTKWKELRHFSLMT 130

  Fly   148 LKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGI 212
            |:..||.:|      .:|.||.   :|...|.: |.:|:..|..:|...|..:..|:|..:||..
  Rat   131 LRNFGMGKR------SIEDRIQ---EEASCLVE-ELRKTNGSLCDPTFILSCAPSNVICSVVFHN 185

  Fly   213 TYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLR---HLPANVRNIRFLLEGKAKTHAIYDRI 274
            .:...|.::|.|.....|..|::.       .||::   .|||.:.    .|.|.      ::|:
  Rat   186 RFDYKDENFLNLMEKLNENFKILN-------SPWMQVCNALPAFID----YLPGS------HNRV 233

  Fly   275 VEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESD------EED 333
            :           |.|.|::..          .||:.||   .||..:.|...:..|      |::
  Rat   234 I-----------KNFAEIKSY----------ILRRVKE---HQETLDMDNPRDFIDCFLIKMEQE 274

  Fly   334 TYEP--ECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRL 396
            .:.|  |..:|..:|.                ::|:|.||.:|:..|||:.||.|.:......::
  Rat   275 KHNPRTEFTIESLMAT----------------VSDVFVAGSETTSTTLRYGLLLLLKHTEVTAKV 323

  Fly   397 HELL---LPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIV 458
            .|.:   :.....|.:::...:.|..|.:.|..|..:::|..:||....|....:|.|..|:.:|
  Rat   324 QEEIDHVIGRHRRPCMQDRTRMPYTDAMVHEIQRYINLIPNNVPHAATCNVRFRNYVIPKGTDLV 388

  Fly   459 CSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRIL 523
            .|..::..|...||.||.|.|..||..:|.::....|:|||:|.|||.||.:|||.|.|....|:
  Rat   389 TSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFSTGKRMCVGEALARMELFLLLTTIV 453

  Fly   524 RRFHLELPSGTEVDMAGESGITLTPTPHMLRFTKLP 559
            :.|:|:....|:         .:..||....|.::|
  Rat   454 QNFNLKSFVDTK---------DIDTTPMANTFGRVP 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	120/487 (25%)
Cyp2c24	NP_001258283.1	CYP2C-like	61..485	CDD:410758	123/496 (25%)