Protein Alignment phtm and cyp2a6.9

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001010998.1
• Gene: cyp2a6.9 / 496407
• XenbaseID: XB-GENE-1007450
• Length: 494
• Species: Xenopus tropicalis
• Alignment Length: 559
• Identity: 144/559 - (25%)
• Similarity: 236/559 - (42%)
• Gaps: 84/559 - (15%)

  Fly    11 TGWMPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQK 75
            |.|:.::  |..||:...|:........|:.|     .||||..:|..|.:..:......|||.:
 Frog     3 TSWLWTL--LLCLLISAMLIYSTWNKMYRKRN-----LPPGPTPIPLFGNVMQIKRGEMVKSLIE 60

  Fly    76 LAKRYGGIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWR 138
            |.|:||.|:.|..|..|.|:|.....:::..  :.:..:||..:........|:|::....:.|:
 Frog    61 LGKKYGDIYTLYFGPSPVVILCSYRAIKEALIDQAEEFSGRGAIPSFDQYFQGYGVVFTNGEEWK 125

  Fly   139 HARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGN 203
            :.||.::..|:..||.:|      .:|.||    .|..:....|.|.......:|...|...:.|
 Frog   126 NLRRFSLSTLRNFGMGKR------GIEERI----KEEAQFLVAEIKSYKEKPFDPTNILVQCVSN 180

  Fly   204 IINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVS--GVVNFLP-WLRHLPANVRNIRFLLEGKA 265
            :|..:|||..::..:.|:..|..|.:...:....|  .::|.|| .:.|:|...:||
 Frog   181 VICSVVFGNRFEYANKDFQNLLSLFQSVFQETSSSWGQLLNMLPAVMNHVPGPHKNI-------- 237

  Fly   266 KTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESD 330
                            :::..|:     |...|||..|.|     |..||:
 Frog   238 ----------------IRDMNKL-----EDFVLQRVKENE-----KTVDPN-------------- 262

  Fly   331 EEDTYEPECILEHFL-AVRDTDSQLYCDDQLRHLLA---DLFGAGVDTSLATLRWFLLYLAREQR 391
                 .|..:::.|| .::..:........:::|:|   .:|.||.:|...|||...|.|.....
 Frog   263 -----SPRDLIDSFLIKMQQENKNPTSPFHMKNLIATILSIFFAGTETVSTTLRHGFLILLIHPE 322

  Fly   392 CQRRLHE---LLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKG 453
            .:.:|.|   .::....|||:|:...:.|..|.|.|..|:..|:|:.:||...::.....|.|..
 Frog   323 IEAKLQEEIDRVVGQNRSPTIEDRNKMPYTDAVIHEIQRLSDVIPMNVPHLVTKDTKFRGYTIPK 387

  Fly   454 GSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLF 518
            |:.|.....|:..||..|..|.:|.|..||...|.:::...|:|||:|.|:|.||.:|||.|.||
 Frog   388 GTNIYPLLCAVLRDPEQFDTPSKFNPNHFLDDKGCFKSNDGFMPFSTGKRICLGEGLARMELFLF 452

  Fly   519 TGRILRRFHLELPSG-TEVDMAGE-SGITLTPTPHMLRF 555
            ...||:.|.|...|| ||.::|.: .|....||.:.|.|
 Frog   453 LTNILQNFKLHSESGLTEDNIAPKMKGFANYPTSYQLSF 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	122/485 (25%)
cyp2a6.9	NP_001010998.1	CYP2	65..489	CDD:410652	123/486 (25%)