Protein Alignment phm and Cyp2c54

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_996260.1
• Gene: Cyp2c54 / 404195
• MGIID: 3642960
• Length: 490
• Species: Mus musculus
• Alignment Length: 552
• Identity: 149/552 - (26%)
• Similarity: 235/552 - (42%)
• Gaps: 97/552 - (17%)

  Fly    29 LVLVILYLC------ERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELK 87
            ||||:...|      .||..: .|..||||..||.:|.:..:|.:...:|...|::.||.::.|.
Mouse     5 LVLVLTLSCLFLLSLWRQSYE-RGKLPPGPTPLPIIGNILQIDVKDICQSFTNLSRVYGPVYTLY 68

  Fly    88 MGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKA 150
            :||.|||||.....|::..  ..||..||..|.:......|.||..:...:|::.|..::..|:.
Mouse    69 LGRKPTVVLHGYEAVKEALVDHGDVFAGRGRLPVFDKATNGMGIGFSNGSVWKNTRHFSLMTLRN 133

  Fly   151 LGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYK 215
            |||.:|..|.|          |.|..|....|.:|:..|..:|...|..:..|:|..::|...:.
Mouse   134 LGMGKRSIEDR----------VQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICSIIFQDRFD 188

  Fly   216 RDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLR---HLPANVRNIRFLLEGKAKTHAIYDRIVEA 277
            ..|.|:|.|....:|..|::..       |||:   ..||       ||:....:|
Mouse   189 YKDRDFLNLLEKLDEISKILST-------PWLQVCNTFPA-------LLDYCPGSH--------- 230

  Fly   278 CGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILE 342
                    .:.||.....|..  .|||  :|:.||:                  .|...|...::
Mouse   231 --------NQFFKNYAYIKNF--LLEK--IREHKES------------------LDVTIPRDFID 265

  Fly   343 HFL---AVRDTDSQLYCDDQLRHL---LADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELL- 400
            :||   |..|.:..|  .:...||   :.|||..|.::...|||:.||.|.:......::.|.:
Mouse   266 YFLIKGAQEDDNHPL--KNNFEHLAITVTDLFIGGTESMSTTLRYALLLLLKYPHVTAKVQEEIE 328

  Fly   401 --LPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWA 463
              :.....|.:::...:.|..|.|.|..|...:||..:||....:....:|||..|:.::.|..:
Mouse   329 HVIGKHRRPCMQDRSHMPYTNAMIHEVQRFIDLVPNNLPHEVTCDIKFRNYFIPKGTTVITSLSS 393

  Fly   464 IHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHL 528
            :..|...||.||:|.|..||..:|.::....|:|||:|.|:|.||.:|||.|.||...||:.|:|
Mouse   394 VLRDSKEFPNPEKFDPGHFLDENGKFKKSDYFMPFSTGKRICAGEGLARMELFLFLTSILQNFNL 458

  Fly   529 E-LPSGTEVDMAGESGITLTPTPHMLRFTKLP 559
            : |....::|:          ||.::....:|
Mouse   459 KPLVHPKDIDI----------TPMLIGLGSVP 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	140/520 (27%)
Cyp2c54	NP_996260.1	p450	30..487	CDD:278495	141/526 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000