Protein Alignment phtm and cyp2k18

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_005163790.1
• Gene: cyp2k18 / 393484
• ZFINID: ZDB-GENE-040426-1584
• Length: 503
• Species: Danio rerio
• Alignment Length: 567
• Identity: 157/567 - (27%)
• Similarity: 252/567 - (44%)
• Gaps: 96/567 - (16%)

  Fly    14 MPSVQSL----SILLVPGALVL-VILYLCER-QCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKS 72
            |..|:||    |...:.|||:| ::|||... ..:...|..||||..||.||.|..||......:
Zfish     1 MAVVESLLQFASTGTLLGALLLFLVLYLVSSGSGSQKEGKEPPGPKPLPLLGNLLTLDLTRAFDT 65

  Fly    73 LQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGIMGGF-------GII 130
            ..:|:|.||.||::.:|...||||.....|     ::.:...|..:....|...|       ||:
Zfish    66 FFELSKTYGNIFQVYLGPKKTVVLVGYKTV-----KEALVNHAEAFGDREIGPSFRIMNDEHGIV 125

  Fly   131 CAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDT-EAKKSCASEVNPL 194
            .:..:.|:..||..:..|:..||.:|..      |.:|...:......||. |.|....:|
Zfish   126 FSNGENWKEMRRFALSNLRDFGMGKRGS------EEKIIEEIHHLKGEFDKFEGKPFDTTE---- 180

  Fly   195 PALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIG-VS-GVVNFLPWLRHLPANVRNI 257
             .:::::.|||:.:|:|..::..||.:..:.....|.|::.| :| |:.|..|||
Zfish   181 -PVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMGLYNMFPWL---------- 234

  Fly   258 RFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEA 322
                                 |..||.|:.|.:.:.:.:   .|:.|......:..:|:..:...
Zfish   235 ---------------------GPFLKNKRIVVRNIIQSR---AQMTKLITALLETLNPNDPRGFV 275

  Fly   323 DE------DDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRW 381
            |.      .||:|.::::|                   :.::.|...:|:||.||.||:..||||
Zfish   276 DSFLIHKLSDEKSGKKNSY-------------------FHNENLMMNVANLFVAGTDTTGTTLRW 321

  Fly   382 FLLYLAREQRCQRRLHELLLPL--GPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENF 444
            .|:.:|:..:.|.|:.|.:..:  |..|.:|:.:.|.|..|.|.|..|..::|||.:||....:.
Zfish   322 GLMLMAKYPQIQDRVQEEIDRVIGGRQPAVEDRKKLPYTDAVIHEIQRFANIVPLNLPHTTSCDI 386

  Fly   445 VVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEE 509
            ....||||.|:.::....::..|...:.:|..|.||.||...|.:.....|:|||:|.|:|.||.
Zfish   387 TFNGYFIKKGTTVIPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSAGRRICLGES 451

  Fly   510 MARMILTLFTGRILRRFHLELPSGT---EVDMAGESGITLTPTPHML 553
            :|||.|.||...:|:.:....|.|.   |:|:.|..||||.|:||.|
Zfish   452 LARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	129/492 (26%)
cyp2k18	XP_005163790.1	cytochrome_P450	73..498	CDD:477761	130/493 (26%)