Protein Alignment phtm and cyp2aa3

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_938183.2
• Gene: cyp2aa3 / 386638
• ZFINID: ZDB-GENE-031030-8
• Length: 496
• Species: Danio rerio
• Alignment Length: 546
• Identity: 152/546 - (27%)
• Similarity: 242/546 - (44%)
• Gaps: 90/546 - (16%)

  Fly    19 SLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLP-FLDARAPHKSLQKLAKRYGG 82
            |:.:.|..|.::||:..:.  :.:......||||..|||:|.:| ||  :.|...::.:: :||.
Zfish    12 SVGLTLFLGLIILVLFEIF--RIHSYKRRTPPGPTPLPFVGTIPHFL--KNPLGFIRSMS-QYGD 71

  Fly    83 IFELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGIMGGFGI-ICAQEDIWRHARRETID 146
            :..:.:||.|.:.|:...|.::...:|..:|:..|.:...|..|||| :......||..||..:.
Zfish    72 MSTMYLGRKPAIFLNTIQLAKETLVQDTFSGKPYLPVIEWISKGFGIAMVTFNHSWRQQRRFALH 136

  Fly   147 WLKALGMTRRPGELRARLERR--IARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLV 209
            .||..|:.::..|.|...|.|  ||            |..|.....|:|...:.:::.|||..:|
Zfish   137 TLKNFGLGKKSVEDRVLEESRYLIA------------EMLKDEGKPVDPHHPIQNAVSNIICSIV 189

  Fly   210 FGITYKRDDPDWLYLQRLQEEGVKLIG-VSG-VVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYD 272
            ||..::.::..:.||.::..|.:.|.| .|| :.|.:|:::|.|...:.|      |..|    |
Zfish   190 FGDRFEYNNKRFEYLLKMLNETIMLAGSASGRIFNLVPFIKHFPGPHQKI------KKNT----D 244

  Fly   273 RIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEP 337
            .::...|..::|.:|..                        ||...:          |..|.|
Zfish   245 DLLIFLGDEVEEHRKTL------------------------DPGSPR----------DFIDAY-- 273

  Fly   338 ECILEHFLAVRDTDSQLYCDDQLRH---LLA---DLFGAGVDTSLATLRWFLLYLAREQRCQRRL 396
              :||       .:.|.:..|...|   |||   |||.||.||:..|:||.||:|.:....|.|.
Zfish   274 --LLE-------IEKQKFNKDSTFHEGNLLASAGDLFMAGTDTTETTIRWGLLFLIQNPDVQERC 329

  Fly   397 H-ELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIV 458
            | |::..||..  |::::.:.|.|..|.:.|..|..:::|:.|........:.| |.|..|:.||
Zfish   330 HEEIVQVLGYDRLPSMDDRDRLPYTLATVHEIQRYGNIIPILIHETILPTKLQG-YSIPQGTTIV 393

  Fly   459 CSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRIL 523
            .:..||......:..|:.|.||.|| .|..:..|..||.||.|.|.|.||.:||..|.||...:|
Zfish   394 TNIQAIFSSKDHWKHPDSFNPENFL-EDRHFIKPESFIMFSLGPRSCLGEILARTELFLFITSLL 457

  Fly   524 RRFHLELPSGTE-VDMAGESGITLTP 548
            :|.|...|...: :||.|..|:..:|
Zfish   458 QRIHFSWPPDAKPIDMDGIFGLVHSP 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	134/483 (28%)
cyp2aa3	NP_938183.2	cytochrome_P450	69..488	CDD:477761	135/484 (28%)