Protein Alignment phtm and Cyp2t4

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001093654.1
• Gene: Cyp2t4 / 384724
• MGIID: 2686296
• Length: 503
• Species: Mus musculus
• Alignment Length: 577
• Identity: 154/577 - (26%)
• Similarity: 249/577 - (43%)
• Gaps: 116/577 - (20%)

  Fly    17 VQSLSILLVPGALVLVILY----LCERQC---NDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQ 74
            |..|::||:  .|:|::|.    :..||.   .||    ||||..||.||.|..|.:....:.|.
Mouse    10 VTCLALLLL--LLILMLLLWWGGVVRRQAQMQKDL----PPGPAPLPLLGNLLQLQSGDLDRVLM 68

  Fly    75 KLAKRYGGIFELKMGRVPTVVLSDAALVRD--FFRRDVMTGRAPLYLTHGIMGGFGIICAQEDIW 137
            :|:..:|.:|.:.:|.:|.|||.....:||  ..:.|..:||..:.:......|.||:.:....|
Mouse    69 ELSSHWGPVFTVWLGPLPAVVLCGYEALRDALVLQADAFSGRGAMAVFDRFTCGNGIVFSNGPRW 133

  Fly   138 RHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLG 202
             |:.|..     |||:.|..|..|:.:|.||   ::|...:.| |.:.:..:..:|...|..::.
Mouse   134 -HSLRNF-----ALGVLRELGVGRSTIEDRI---LEEAACVLD-EFQATMGAPFDPQQLLDSAVS 188

  Fly   203 NIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGV--SGVVN----FLPWLRHLPANVRNIRFLL 261
            |:|..:|||..|...||::..|..|..:...::..  :.:.|    |:.|:.. |.|
Mouse   189 NVICTVVFGKRYDYGDPEFRRLLNLFSDNFCIMSSRWAEIYNMFPSFMDWIPG-PHN-------- 244

  Fly   262 EGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLR---QSKEADPSQEQSEAD 323
                                     ::||..||    .|....||::   ||::
Mouse   245 -------------------------RIFKNFQE----LRLFISEQIQWHWQSRQ----------- 269

  Fly   324 EDDEESDEEDTYEPECILEHFLAVRDTDSQ----LYCDDQLRHLLADLFGAGVDTSLATLRWFLL 384
                      |.||...::.||...|.:.|    .:.|:.|.....|||..|.:|:..|||:.||
Mouse   270 ----------TGEPRDFIDCFLDQMDKEQQDLESHFQDETLVMTTHDLFFGGTETTSTTLRYGLL 324

  Fly   385 YLAREQRCQRRLHELL-LPLGP--SPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVV 446
            .:.:......::.|.| ..:|.  :|.:|:...|.|..|.:.|..|..||:|||:|.....:..:
Mouse   325 IMLKYPEVAAKVQEELDATVGRTWAPRIEDRARLPYTNAVLHEIQRFISVLPLGLPRALTRDVNL 389

  Fly   447 GDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMA 511
            .::|:..|:.::....:.|.||..|.:|:.|.|..||...|.:|....|:||:.|.|||.|..:|
Mouse   390 KNHFLHKGTFVIPLLVSAHRDPTQFKDPDHFNPTNFLDDHGEFQNNDAFMPFALGKRMCLGAGLA 454

  Fly   512 RMILTLFTGRILRRFHLELPSGTEVDMAGESGITLTPTPHMLRFTKL----PAVEMR 564
            |..:.||...||::|.| ||.|:      .:.|.|.|     :.|.|    ||.::|
Mouse   455 RSEIFLFLTAILQKFSL-LPVGS------PANINLNP-----QCTGLGNVPPAFQLR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	126/489 (26%)
Cyp2t4	NP_001093654.1	Cyp2F	74..498	CDD:410762	130/504 (26%)