Protein Alignment phtm and Cyp2j3

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_786942.1
• Gene: Cyp2j3 / 313375
• RGDID: 631442
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 139/563 - (24%)
• Similarity: 241/563 - (42%)
• Gaps: 101/563 - (17%)

  Fly    13 WMPSVQSLSILLVPGALVLVIL-YLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKL 76
            |  :|..|.|||:.....|.:. :|..|:..:.    |||||.||.:|.|..||.:.||.|||:.
  Rat    13 W--TVLHLRILLLAAVTFLFLADFLKHRRPKNY----PPGPWRLPLVGCLFHLDPKQPHLSLQQF 71

  Fly    77 AKRYGGIFELKMGRVPTVVLSDAALVRD--------FFRRDVMTGRAPLYLTHGIMGGFGIICAQ 133
            .|:||.:..|....:|:||::...|:::        |..|.|...|..|:..:|::...|
  Rat    72 VKKYGNVLSLDFANIPSVVVTGMPLIKEIFTQMEHNFLNRPVTLLRKHLFNKNGLIFSSG----- 131

  Fly   134 EDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALH 198
             ..|:..||..:..|:..|:.::      .||:||.   :|...|.:. .|.......:|...::
  Rat   132 -QTWKEQRRFALMTLRNFGLGKK------SLEQRIQ---EEAYHLVEA-IKDEGGLPFDPHFNIN 185

  Fly   199 HSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIG--VSGVVNFLP-WLRHLP-------AN 253
            .::.|||..:.||..::..|..:..:.||.:|.:.|..  :..:.|..| .|::||       :|
  Rat   186 KAVSNIICSVTFGERFEYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQYLPGSHQTLFSN 250

  Fly   254 VRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQE 318
            .|.::..:....|.|                                         .::.||
  Rat   251 WRKLKLFISDIIKNH-----------------------------------------RRDWDP--- 271

  Fly   319 QSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFL 383
                   ||..|..|.:     |:......|..:..:.::.|.....|||.||.:|:..||||.|
  Rat   272 -------DEPRDFIDAF-----LKEMAKYPDKTTTSFNEENLICSTLDLFFAGTETTSTTLRWAL 324

  Fly   384 LYLAREQRCQRRLH---ELLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFV 445
            |.:|.....|.::.   :.::..|..|.|.:.:.:.|..|.|.|..||.:::|..:|.....:..
  Rat   325 LCMALYPEVQEKMQAEIDRVIGQGRQPNLADRDSMPYTNAVIHEVQRIGNIIPFNVPREVAVDTY 389

  Fly   446 VGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEM 510
            :..:.:..|:||:.:..|:|.||..:..|:.|.||.|| .:|.::....|:|||.|.|.|.||::
  Rat   390 LAGFNLPKGTMILTNLTALHRDPKEWATPDTFNPEHFL-ENGQFKKRESFLPFSMGKRACLGEQL 453

  Fly   511 ARMILTLFTGRILRRFHLELPSGTEVDMAGESGITLTPTPHML 553
            ||..|.:|...::::|..:.|...::.:.....:|::|..|.|
  Rat   454 ARSELFIFITSLIQKFTFKPPVNEKLSLQFRMSVTISPVSHRL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	111/492 (23%)
Cyp2j3	NP_786942.1	CYP2J	75..496	CDD:410755	112/493 (23%)