Protein Alignment phtm and Cyp2j10

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001128452.2
• Gene: Cyp2j10 / 313373
• RGDID: 1563215
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 138/541 - (25%)
• Similarity: 239/541 - (44%)
• Gaps: 72/541 - (13%)

  Fly    21 SILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFE 85
            ::||.....:.:..||..|:..:.    |||||.|||:|.|..||.:.||..:||..|:||.:..
  Rat    20 TLLLAAVTFLFLANYLKTRRPKNY----PPGPWRLPFVGNLFQLDVKQPHVVIQKFVKKYGNLTS 80

  Fly    86 LKMGRVPTVVLSDAALVRDFFRRDVMT--GRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWL 148
            |..|.:|:||::...|:::.|......  .|....|...:....|:|.:....|:..||.|:..|
  Rat    81 LDFGTIPSVVITGLPLIKEAFTNTEQNFLNRPVTPLRKRVFNNNGLIMSNGQTWKEQRRFTMTTL 145

  Fly   149 KALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGIT 213
            |..|:.:|      .||:||....:..|.....:.    ....:|...::.::.|||..:.||..
  Rat   146 KNFGLGKR------SLEQRIQEEANYLVEAIGADK----GQPFDPHFKINSAVSNIICSITFGER 200

  Fly   214 YKRDDPDWLYLQRLQEEGVKLIG--VSGVVNFLPW-LRHLPANVRNIRFLLEGKAKTHAIYDRIV 275
            ::.:|..:..|.||.:|...|..  :..:.|..|. :::||.:.:.:
  Rat   201 FEYEDSLFQELLRLLDEASCLESSMMCQLYNVFPTIIKYLPGSHQTV------------------ 247

  Fly   276 EACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECI 340
                .|..||.|:|        :...::..|    |:.:|          ||..|..|.:
  Rat   248 ----LRNWEKLKLF--------ISCMMDSHQ----KDWNP----------DEPRDFIDAF----- 281

  Fly   341 LEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLH-ELLLPLG 404
            |......||..:..:..:.|.:...|||.||.:|:...|||.|||:......|.::| |:...:|
  Rat   282 LTEMAKYRDKTTTSFNKENLIYSTLDLFFAGSETTSNILRWSLLYITTNPEVQEKVHSEIDRVIG 346

  Fly   405 --PSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMD 467
              ..|:..:.:.:.|..|.|.|.:|:.:::||.:|.....:..:..:.:..|:.|:.:...:|.|
  Rat   347 HRRQPSTGDRDAMPYTNAVIHEVLRMGNIIPLNVPREMTADSTLAGFHLPKGTTILTNLTGLHRD 411

  Fly   468 PVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPS 532
            |..:..|:.|.||.|| .:|.::....|:|||.|.|.||||::||..|.:|...:::.|..:.|.
  Rat   412 PKEWATPDTFNPEHFL-ENGQFKKRDSFLPFSMGKRACPGEQLARTELFIFFTALMQNFTFKPPV 475

  Fly   533 GTEVDMAGESGITLTPTPHML 553
            ...:.:...:|:||.|..|.:
  Rat   476 NETLSLKFRNGLTLAPVSHRI 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	115/479 (24%)
Cyp2j10	NP_001128452.2	cytochrome_P450	75..496	CDD:477761	116/480 (24%)