Protein Alignment phtm and Cyp2u1

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001380742.1
• Gene: Cyp2u1 / 310848
• RGDID: 1309433
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 576
• Identity: 160/576 - (27%)
• Similarity: 257/576 - (44%)
• Gaps: 98/576 - (17%)

  Fly    15 PSVQSL-SILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFL-------------- 64
            |.:|:: ..||:.|..||:.....:||   ..|..||||...|.:|...:|
  Rat    19 PHLQAVGGALLLCGLAVLLDWVWLQRQ---RAGGIPPGPKPRPLVGNFGYLLLPRFLRLHFWLGS 80

  Fly    65 ----DARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGI 123
                |....|..|.:||:.||.||...:|....|||||...||:..  :.:|.:.|..:.|...:
  Rat    81 GSQTDTVGRHVYLARLARVYGNIFSFFIGHRLVVVLSDFQSVREALVQQAEVFSDRPRMPLISIL 145

  Fly   124 MGGFGIICAQ-EDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSC 187
            ....||:.|. ..||:..||.:...|:..|:    |:|  .||.||   ::|...: ..|.:|..
  Rat   146 TKEKGIVFAHYGPIWKQQRRFSHSTLRHFGL----GKL--SLEPRI---IEEFAYV-KAEMQKHG 200

  Fly   188 ASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSG--VVNFLPWLRHL 250
            .:..:|.|.:.:::.|||..|.||..:...:.::..:......|:::...|.  ::|..||..:|
  Rat   201 EAPFSPFPVISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINLCPWFYYL 265

  Fly   251 PANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEA-D 314
            |..                                  .||||::.:|......|..:::.:|: |
  Rat   266 PFG----------------------------------PFKELRQIERDITCFLKNIIKEHQESLD 296

  Fly   315 PSQEQSEAD----EDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTS 375
            .:..|...|    ...||.|       :|        :.|:   :.:|.|.:::.|||.||.||:
  Rat   297 ANNPQDFIDMYLLHTQEEKD-------KC--------KGTN---FDEDYLFYIIGDLFIAGTDTT 343

  Fly   376 LATLRWFLLYLAREQRCQRRLH---ELLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIP 437
            ..:|.|.|||::.....|:::|   |.::....:|:|.:...:.|..|.|.|..|:..||||.||
  Rat   344 TNSLLWCLLYMSLNPGVQKKVHEEIERVIGRDRAPSLTDKAQMPYTEATIMEVQRLSMVVPLAIP 408

  Fly   438 HGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGY 502
            |...|..|:..|.|..|::::.:.|:||.|||.:.:|::|.|.|||...|.......||||..|.
  Rat   409 HMTSEKTVLQGYSIPKGTVVLPNLWSIHRDPVIWEKPDDFCPHRFLDDQGQLLKRETFIPFGIGK 473

  Fly   503 RMCPGEEMARMILTLFTGRILRRFHLELPSGTEVD-MAGESGITLTPTPHMLRFTK 557
            |:|.||::|:|.|.|....:::.|...||.|:|.. |.|..|:||.|.|..:..:|
  Rat   474 RVCMGEQLAKMELFLMFVSLMQSFTFALPEGSEKPIMTGRFGLTLAPHPFNVTVSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	136/485 (28%)
Cyp2u1	NP_001380742.1	CYP2U1	100..525	CDD:410759	137/486 (28%)