Protein Alignment phtm and Cyp2s1

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001100965.1
• Gene: Cyp2s1 / 308445
• RGDID: 1306078
• Length: 499
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 148/551 - (26%)
• Similarity: 231/551 - (41%)
• Gaps: 119/551 - (21%)

  Fly    14 MPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAK 78
            |.:..:.::||   ||:|::|.|...: ....|..||||..||.||.|..|...|.:....:|:|
  Rat     1 MEAASTWALLL---ALLLLLLALTLPR-TPARGQLPPGPTPLPLLGNLLQLRPGALYSGFLRLSK 61

  Fly    79 RYGGIFELKMG---RVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWR 138
            :||.:|.:.:|   ||..:|..||  :|:..  :.:..:||..|........|.|:..|..:.|:
  Rat    62 KYGPVFTVHLGPWRRVVVLVGHDA--IREALGGQAEEFSGRGTLATLDKTFDGHGVFFANGERWK 124

  Fly   139 HARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFD-TEAKKSCASEVNPLPALHHSLG 202
            ..|:.|:..|:.|||.:|.|      |..|...|...|:.|. ||.:     ..||...|..:..
  Rat   125 QLRKFTLLALRDLGMGKREG------EELIQEEVQNLVKAFQRTEGR-----PFNPSMLLAQATS 178

  Fly   203 NIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPW----------LRHLPANVRNI 257
            |::..|:|||....:|.::..:  :|.....|:|:|.     ||          |:.||.....:
  Rat   179 NVVCSLIFGIRLPYEDKEFQAV--IQAASGTLLGISS-----PWGQAYEMFSWLLQPLPGPHTQL 236

  Fly   258 RFLL--------------EGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLR 308
            :..|              :|::.|......:|:|..|::.:                  |||
  Rat   237 QHHLGTLAAFTIQQVQRHQGRSHTSGPARDVVDAFLQKMAQ------------------EKE--- 280

  Fly   309 QSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVD 373
                 ||..|                                    :.:..|...:..|..||..
  Rat   281 -----DPGTE------------------------------------FTEKNLLMTVTYLLFAGTM 304

  Fly   374 TSLATLRWFLLYLAREQRCQRRL-HELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLG 435
            |..||:|:.||.|.:..:.|:|: .||:..||||  |:|.:...|.|..|.:.|..|:.::||:|
  Rat   305 TIGATIRYALLLLLKYPQVQKRVREELIQELGPSRTPSLSDRVRLPYTDAVLHEAQRLLALVPMG 369

  Fly   436 IPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSS 500
            :||...:......|.:..|:.:.....::..||..|..||||.|.|||..||..:....|:|:|.
  Rat   370 MPHTVTKTTSFRGYTLPKGTEVFPLIGSVLHDPAVFRNPEEFHPSRFLDDDGRIRKHEAFLPYSL 434

  Fly   501 GYRMCPGEEMARMILTLFTGRILRRFHLELP 531
            |.|:|.||.:||..|.||...||:.|.|:.|
  Rat   435 GKRVCLGEGLARAELWLFFTSILQAFSLDTP 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	125/484 (26%)
Cyp2s1	NP_001100965.1	CYP2	63..489	CDD:410652	126/485 (26%)