Protein Alignment phm and Cyp2c7

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_058854.1
• Gene: Cyp2c7 / 29298
• RGDID: 620379
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 137/549 - (24%)
• Similarity: 234/549 - (42%)
• Gaps: 83/549 - (15%)

  Fly    22 ILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFEL 86
            ::|...:|:|:.|:....:...|    ||||..||.:|....:|.:...:||.|.:|.||.:|.|
  Rat     7 LVLTLSSLILLSLWRQSSRRRKL----PPGPTPLPIIGNFLQIDVKNISQSLTKFSKTYGPVFTL 67

  Fly    87 KMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLK 149
            .:|..|||:|.....:::..  ..:..:||....:...:..||||:.:..:.|:..||.||...:
  Rat    68 YLGSQPTVILHGYEAIKEALIDNGEKFSGRGSYPMNENVTKGFGIVFSNGNRWKEMRRFTIMNFR 132

  Fly   150 ALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITY 214
            .||:.:|      .:|.|    |.|..:....|.:|:..|..:|...|:.:..|:|..:.|...:
  Rat   133 NLGIGKR------NIEDR----VQEEAQCLVEELRKTKGSPCDPSLILNCAPCNVICSITFQNHF 187

  Fly   215 KRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLR---HLPANVRNIRFLLEGKAKTHAIYDRIVE 276
            ...|.:.|.......|.:|::.       .||::   ..|:       |::....||
  Rat   188 DYKDKEMLTFMEKVNENLKIMS-------SPWMQVCNSFPS-------LIDYFPGTH-------- 230

  Fly   277 ACGQRLKEKQKVFKELQEQKR-LQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECI 340
                     .|:.|.:...|. |.:::|:.|                       :..|...|...
  Rat   231 ---------HKIAKNINYMKSYLLKKIEEHQ-----------------------ESLDVTNPRDF 263

  Fly   341 LEHFL----AVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHE--- 398
            ::::|    ...:.:...|..:.|...:.||.|||.:|...|||:.||.|.:......::.|
  Rat   264 VDYYLIKQKQANNIEQSEYSHENLTCSIMDLIGAGTETMSTTLRYALLLLMKYPHVTAKVQEEID 328

  Fly   399 LLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWA 463
            .::....||.:::.:.:.|..|.|.|..|..:.||..:||....:....:|.|..|:.::.|..:
  Rat   329 RVIGRHRSPCMQDRKHMPYTDAMIHEVQRFINFVPTNLPHAVTCDIKFRNYLIPKGTKVLTSLTS 393

  Fly   464 IHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHL 528
            :..|...||.||.|.|..||..:|.::....|:|||:|.|.|.||.:|||.|.||...||:.|:|
  Rat   394 VLHDSKEFPNPEMFDPGHFLDENGNFKKSDYFLPFSAGKRACVGEGLARMQLFLFLTTILQNFNL 458

  Fly   529 E-LPSGTEVD-MAGESGITLTPTPHMLRF 555
            : |....::| |...:|....|..:.|.|
  Rat   459 KSLVHPKDIDTMPVLNGFASLPPTYQLCF 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	131/520 (25%)
Cyp2c7	NP_058854.1	p450	30..487	CDD:278495	131/520 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000