Protein Alignment phm and Cyp2b21

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_942028.1
• Gene: Cyp2b21 / 292728
• RGDID: 735174
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 155/564 - (27%)
• Similarity: 243/564 - (43%)
• Gaps: 101/564 - (17%)

  Fly    15 PSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKR 79
            |||..|..||. |.|:|:|     |...:..|..||||..||.||.:..:|.|...||..:|..:
  Rat     3 PSVLLLFALLT-GFLLLLI-----RGQGNGYGHLPPGPCPLPLLGNVLQMDRRGLLKSFIQLRDK 61

  Fly    80 YGGIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARR 142
            ||.:..:.:|..|.|:|.....:|:..  ..:..:||..:.:...|:..:|:|.|..:.|:..||
  Rat    62 YGDVVTVHLGPRPIVMLYGTETIREALVDHAEAFSGRGTVAVVQPIIQDYGMIFANGERWKILRR 126

  Fly   143 ETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIIND 207
            .::..::..||.:|..|.|.:.|.       :|:   ..|.||...:.::|...|.....|||..
  Rat   127 FSLATMRDFGMGKRSVEERIKEEA-------QCL---VEELKKYKGAPLDPTFHLQCITANIICS 181

  Fly   208 LVFGITYKRDDPDWLYLQRLQEEGVKLIG---------VSGVVNFLPWL-RHLPANVRNI-RFLL 261
            :|||..:...|..:|:|..|..|.:.|:.         .:|.:.:.|.. ||:..|:..| .|:
  Rat   182 IVFGERFDYTDHQFLHLLDLFYEILSLVSSFSSQVFELFTGFLKYFPGTHRHISKNIEEILNFI- 245

  Fly   262 EGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDD 326
                 .|.:             ||.:.                       ..|||..:
  Rat   246 -----GHCV-------------EKHRA-----------------------TLDPSTPR------- 262

  Fly   327 EESDEEDTY----EPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRW-FLLYL 386
               |..|||    |.|.:..|        ::.:..:.:..:|: ||.||.:||..|||: |||.|
  Rat   263 ---DFIDTYLLRMEKEKLNHH--------TEFHHQNLMMSVLS-LFFAGTETSSTTLRYGFLLML 315

  Fly   387 AREQRCQRRLHELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDY 449
            ......::...|:...:|..  |||::...:.|..|.|.|..|...:||:|:||...::.:...|
  Rat   316 KYPHVAEKVQKEIDQVIGSHRVPTLDDRIKMPYTDAVIHEIQRFSDLVPIGLPHRVTKDTLFRGY 380

  Fly   450 FI-KGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARM 513
            .: |...:......|:| ||..|..|:.|.||.||.|:||.:....|:|||:|.|:|.||.:||.
  Rat   381 LLPKNIEVYPILSSALH-DPQYFEHPDTFNPEHFLDANGALKKNEAFLPFSTGKRVCLGEGIARN 444

  Fly   514 ILTLFTGRILRRFHLELP-SGTEVDMA-GESGITLTPTPHMLRF 555
            .|.||...||:.|.:..| |..::|:. .|||....|..:.:.|
  Rat   445 ELFLFFTTILQNFSVSSPVSPKDIDLTPKESGFAKIPPTYQICF 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	142/528 (27%)
Cyp2b21	NP_942028.1	p450	42..488	CDD:278495	134/517 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000