Protein Alignment phtm and Cyp2b21

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_942028.1
• Gene: Cyp2b21 / 292728
• RGDID: 735174
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 155/564 - (27%)
• Similarity: 243/564 - (43%)
• Gaps: 101/564 - (17%)

  Fly    15 PSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKR 79
            |||..|..||. |.|:|:|     |...:..|..||||..||.||.:..:|.|...||..:|..:
  Rat     3 PSVLLLFALLT-GFLLLLI-----RGQGNGYGHLPPGPCPLPLLGNVLQMDRRGLLKSFIQLRDK 61

  Fly    80 YGGIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARR 142
            ||.:..:.:|..|.|:|.....:|:..  ..:..:||..:.:...|:..:|:|.|..:.|:..||
  Rat    62 YGDVVTVHLGPRPIVMLYGTETIREALVDHAEAFSGRGTVAVVQPIIQDYGMIFANGERWKILRR 126

  Fly   143 ETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIIND 207
            .::..::..||.:|..|.|.:.|.       :|:   ..|.||...:.::|...|.....|||..
  Rat   127 FSLATMRDFGMGKRSVEERIKEEA-------QCL---VEELKKYKGAPLDPTFHLQCITANIICS 181

  Fly   208 LVFGITYKRDDPDWLYLQRLQEEGVKLIG---------VSGVVNFLPWL-RHLPANVRNI-RFLL 261
            :|||..:...|..:|:|..|..|.:.|:.         .:|.:.:.|.. ||:..|:..| .|:
  Rat   182 IVFGERFDYTDHQFLHLLDLFYEILSLVSSFSSQVFELFTGFLKYFPGTHRHISKNIEEILNFI- 245

  Fly   262 EGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDD 326
                 .|.:             ||.:.                       ..|||..:
  Rat   246 -----GHCV-------------EKHRA-----------------------TLDPSTPR------- 262

  Fly   327 EESDEEDTY----EPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRW-FLLYL 386
               |..|||    |.|.:..|        ::.:..:.:..:|: ||.||.:||..|||: |||.|
  Rat   263 ---DFIDTYLLRMEKEKLNHH--------TEFHHQNLMMSVLS-LFFAGTETSSTTLRYGFLLML 315

  Fly   387 AREQRCQRRLHELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDY 449
            ......::...|:...:|..  |||::...:.|..|.|.|..|...:||:|:||...::.:...|
  Rat   316 KYPHVAEKVQKEIDQVIGSHRVPTLDDRIKMPYTDAVIHEIQRFSDLVPIGLPHRVTKDTLFRGY 380

  Fly   450 FI-KGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARM 513
            .: |...:......|:| ||..|..|:.|.||.||.|:||.:....|:|||:|.|:|.||.:||.
  Rat   381 LLPKNIEVYPILSSALH-DPQYFEHPDTFNPEHFLDANGALKKNEAFLPFSTGKRVCLGEGIARN 444

  Fly   514 ILTLFTGRILRRFHLELP-SGTEVDMA-GESGITLTPTPHMLRF 555
            .|.||...||:.|.:..| |..::|:. .|||....|..:.:.|
  Rat   445 ELFLFFTTILQNFSVSSPVSPKDIDLTPKESGFAKIPPTYQICF 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	128/494 (26%)
Cyp2b21	NP_942028.1	CYP2B	62..486	CDD:410765	129/495 (26%)