Protein Alignment phm and Cyp2d1

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_695225.1
• Gene: Cyp2d1 / 266684
• RGDID: 708427
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 141/536 - (26%)
• Similarity: 218/536 - (40%)
• Gaps: 108/536 - (20%)

  Fly    49 PPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFFRRDVMTG 113
            ||||...|.||.|..:|......||.||..|||.:|.|:.|..|.|:::....|::
  Rat    37 PPGPVPWPVLGNLLQVDLSNMPYSLYKLQHRYGDVFSLQKGWKPMVIVNRLKAVQE--------- 92

  Fly   114 RAPLYLTHG----------IMGGFG--------IICAQEDIWRHARRETIDWLKALGMTRRPGEL 160
               :.:|||          |....|        |:.:....||..||.::..|:..||.::
  Rat    93 ---VLVTHGEDTADRPPVPIFKCLGVKPRSQGVILASYGPEWREQRRFSVSTLRTFGMGKK---- 150

  Fly   161 RARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQ 225
              .||..:.:........|..:|.:|    :||...|:.:|.|:|..|:|...::.:||..:.:.
  Rat   151 --SLEEWVTKEAGHLCDAFTAQAGQS----INPKAMLNKALCNVIASLIFARRFEYEDPYLIRMV 209

  Fly   226 RLQEEGVKLIGVSG----VVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQ 286
            :|.||  .|..|||    |:|..|.|..:|           |.|                    .
  Rat   210 KLVEE--SLTEVSGFIPEVLNTFPALLRIP-----------GLA--------------------D 241

  Fly   287 KVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLA----V 347
            |||   |.||.....|:..........||:|                  .|..:.:.|||    .
  Rat   242 KVF---QGQKTFMALLDNLLAENRTTWDPAQ------------------PPRNLTDAFLAEVEKA 285

  Fly   348 RDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRW----FLLYLAREQRCQRRLHELLLPLGPSPT 408
            :......:.|:.||.::.|||.||:.|:..||.|    .:||...::|.|:.:.|::..: ..|.
  Rat   286 KGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQV-RCPE 349

  Fly   409 LEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPE 473
            :.:...:.|..|.|.|..|...:.||.:|.....:..|.|:.|..|:.::.:..::..|...:.:
  Rat   350 MTDQAHMPYTNAVIHEVQRFGDIAPLNLPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEK 414

  Fly   474 PEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSG-TEVD 537
            |..|.||.||.|.|.:.....|:|||:|.|.|.||.:|||.|.||...:|:||...:|.| ....
  Rat   415 PHRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPVGQPRPS 479

  Fly   538 MAGESGITLTPTPHML 553
            ..|.....:.|.|:.|
  Rat   480 THGFFAFPVAPLPYQL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	141/536 (26%)
Cyp2d1	NP_695225.1	p450	37..496	CDD:278495	141/536 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000