Protein Alignment phtm and Cyp2a2

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_036825.1
• Gene: Cyp2a2 / 24895
• RGDID: 2464
• Length: 492
• Species: Rattus norvegicus
• Alignment Length: 566
• Identity: 128/566 - (22%)
• Similarity: 236/566 - (41%)
• Gaps: 99/566 - (17%)

  Fly    20 LSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            |.::::....|:.::.|.:::..:.:   ||||..|||:|....|:.:..:.|:.:|::|||.:|
  Rat     7 LLVVILASLSVMFLVSLWQQKIRERL---PPGPTPLPFIGNYLQLNMKDVYSSITQLSERYGPVF 68

  Fly    85 ELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDW 147
            .:.:|....|||.....|::..  :.:..:||..|...:.:..|:|...:..:..:..||.||..
  Rat    69 TIHLGPRRIVVLYGYDAVKEALVDQAEEFSGRGELPTFNILFKGYGFSLSNVEQAKRIRRFTIAT 133

  Fly   148 LKALGMTRRPGELRARLERRIARGVDECV-----RLFDTEAKKSCASEVNPLPALHHSLGNIIND 207
            |:..|:.:              |.|.||:     .|..| .:.:|.:.::|...|..::.|:||.
  Rat   134 LRDFGVGK--------------RDVQECILEEAGYLIKT-LQGTCGAPIDPSIYLSKTVSNVINS 183

  Fly   208 LVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYD 272
            :|||..:..:|.::|.|..:.:| :.:...|.                           |..:||
  Rat   184 IVFGNRFDYEDKEFLSLLEMIDE-MNIFAASA---------------------------TGQLYD 220

  Fly   273 RIVEACGQRLKEKQKVFKELQEQKRLQRQLEK---EQLRQSKEA-DPSQEQSEADEDDEESDEED 333
            ............:|::.|..|       :||.   |::||:... ||:
  Rat   221 MFHSVMKYLPGPQQQIIKVTQ-------KLEDFMIEKVRQNHSTLDPN----------------- 261

  Fly   334 TYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFG---AGVDTSLATLRWFLLYLAREQRCQRR 395
              .|...::.||.....:..:..:..:.:|:....|   ||..:..:||....|.|.:....:.:
  Rat   262 --SPRNFIDSFLIRMQEEKYVNSEFHMNNLVMSSLGLLFAGTGSVSSTLYHGFLLLMKHPDVEAK 324

  Fly   396 LH---ELLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMI 457
            :|   |.::.....|..|:...:.|.:|.|:|..|..::.|||||....:|.....:|:..|:.:
  Rat   325 VHEEIERVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNLAPLGIPRRIIKNTTFRGFFLPKGTDV 389

  Fly   458 VCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRI 522
            .....::..:|..||..::|.|:.||...|..:....|:|||.|.|.|.|:.:|:|.|.|....|
  Rat   390 FPIIGSLMTEPKFFPNHKDFNPQHFLDDKGQLKKNAAFLPFSIGKRFCLGDSLAKMELFLLLTTI 454

  Fly   523 LRRFHLELPSGTEVDMAGESGITLTPTPHMLRFTK-LPAVEMRHAP 567
            |:.|..:.|...|       .|...|:|  :.||: :|...|...|
  Rat   455 LQNFRFKFPMNLE-------DINEYPSP--IGFTRIIPNYTMSFMP 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	107/488 (22%)
Cyp2a2	NP_036825.1	CYP2A	64..487	CDD:410761	111/500 (22%)