Protein Alignment phm and Cyp2a3

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_036674.1
• Gene: Cyp2a3 / 24299
• RGDID: 2465
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 129/554 - (23%)
• Similarity: 234/554 - (42%)
• Gaps: 91/554 - (16%)

  Fly    22 ILLVPGALVLVILYLCE--RQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            :|||.....|.:|.|..  :| ..|.|..||||..|||:|....|:....:.||.|:::|||.:|
  Rat     6 LLLVASVAFLSVLVLMSVWKQ-RKLSGKLPPGPTPLPFIGNYLQLNTEKMYSSLMKISQRYGPVF 69

  Fly    85 ELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDW 147
            .:.:|....|||.....|::..  :.:..:||........:..|:|:..:..:..:..||.:|..
  Rat    70 TIHLGPRRVVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSSGERAKQLRRFSIAT 134

  Fly   148 LKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGI 212
            |:..|:.:|      .:|.||.......:..|    :|:..:.::|...|..::.|:|:.:|||.
  Rat   135 LRDFGVGKR------GIEERIQEEAGFLIESF----RKTNGALIDPTFYLSRTVSNVISSIVFGD 189

  Fly   213 TYKRDDPDWLYLQRLQEEGVKLIGVS-GVV--NFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRI 274
            .:..:|.::|.|.|:.....:....| |.:  .|...::|||.
  Rat   190 RFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPG---------------------- 232

  Fly   275 VEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPEC 339
                     .:|:.|||||   .|:..:.|:..:..:..||:                   .|..
  Rat   233 ---------PQQQAFKELQ---GLEDFITKKVEQNQRTLDPN-------------------SPRD 266

  Fly   340 ILEHFL-----AVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHE- 398
            .::.||     ..::.:::.|..:.:...| :||.||.:|...|||:..|.|.:....:.::||
  Rat   267 FIDSFLIRMLEEKKNPNTEFYMKNLVLTTL-NLFFAGTETVSTTLRYGFLLLMKHPDIEAKVHEE 330

  Fly   399 --LLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSE 461
              .::........|:...:.|..|.|.|..|...::|:|:.....::....::.:..|:.:....
  Rat   331 IDRVIGRNRQAKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKFREFLLPKGTEVFPML 395

  Fly   462 WAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRF 526
            .::..||..|..|.:|.|:.||...|.::....|:|||.|.|.|.||.:|||.|.||...|::.|
  Rat   396 GSVLKDPKFFSNPNDFNPKHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNF 460

  Fly   527 HLELPSG-TEVDMAGESGITLTPTPHMLRFTKLP 559
            ..:.|.. .::|:          :|.::.|..:|
  Rat   461 CFKSPQAPQDIDV----------SPRLVGFATIP 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	118/519 (23%)
Cyp2a3	NP_036674.1	p450	34..491	CDD:278495	120/525 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000