Protein Alignment phtm and Cyp2j12

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001093652.1
• Gene: Cyp2j12 / 242546
• MGIID: 3717097
• Length: 502
• Species: Mus musculus
• Alignment Length: 545
• Identity: 136/545 - (24%)
• Similarity: 246/545 - (45%)
• Gaps: 84/545 - (15%)

  Fly    24 LVPGALVLVIL--YLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFEL 86
            ||..|:..::|  ||..::..:.    |||||.|||:|.|..||...||..:|:..|:||.:..|
Mouse    21 LVLAAVTFMLLAHYLKTQRPKNY----PPGPWRLPFVGNLFQLDLEQPHVVIQQFVKKYGNLTSL 81

  Fly    87 KMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGI-------MGGFGIICAQEDIWRHARRET 144
            ..|.:|:|:::...|:::.|     |.....:|...|       ....|:|.:....|:..||..
Mouse    82 DFGNIPSVIITGLPLIKEVF-----TNMEQNFLNRPITPIRKRVFNNNGLIISNGQTWKEQRRFA 141

  Fly   145 IDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLV 209
            :..||..|:.::      .||:||.:..|..|.....|.    ....:|...::.::.|||....
Mouse   142 LMTLKNFGLGKK------SLEQRIQKEADCLVEAIGEEK----GQPFDPHFKINSAVSNIICTFA 196

  Fly   210 FGITYKRDDPDWLYLQRLQEEGVKLIG--VSGVVNFLP-WLRHLPANVRNIRFLLEGKAKTHAIY 271
            ||..::.:|..:..|.||.:|...|..  :..:.|..| .::::|.:.:.:
Mouse   197 FGERFEYEDSHFHELLRLLDEATCLEASMMCQLYNVFPSIIQYVPGSHQTV-------------- 247

  Fly   272 DRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYE 336
                    .|..||.|:|        :.:.:|..:    |:.:|          ||..|..|.:
Mouse   248 --------LRNWEKLKLF--------IYQMMESHR----KDWNP----------DEPRDFIDAF- 281

  Fly   337 PECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLH---E 398
                |.......|..:..:.::.|.:...|||.||.:|:..||||.|||:......|.::|   :
Mouse   282 ----LTEMSKYGDKTTTSFNEENLINSTLDLFFAGSETTTNTLRWALLYITTNPEVQEKVHSEID 342

  Fly   399 LLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWA 463
            .::..|..|:.::.:.:.|..|.|.|.:|:.:::|:.:|.....:..:..:.:..|:|::.:..|
Mouse   343 RVIGHGRQPSTDDRDSMPYTNAVIHEVLRMGNILPMNVPREVTADSTLAGFHLPKGTMVLTNLTA 407

  Fly   464 IHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHL 528
            :|.||..:..|..|.||.|| .:|.::....|:|||.|.|.||||::||..|.:|...::::|..
Mouse   408 LHRDPKEWATPNTFNPEHFL-ENGQFKKRESFLPFSLGKRACPGEQLARSELFIFFTALMQKFTF 471

  Fly   529 ELPSGTEVDMAGESGITLTPTPHML 553
            :.|...::.:...:|:||:|..|.:
Mouse   472 KPPINEKLSLKFRNGLTLSPVSHCI 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	113/484 (23%)
Cyp2j12	NP_001093652.1	cytochrome_P450	75..496	CDD:477761	114/485 (24%)