Protein Alignment phm and Cyp2a22

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001094937.1
• Gene: Cyp2a22 / 233005
• MGIID: 3648316
• Length: 492
• Species: Mus musculus
• Alignment Length: 559
• Identity: 125/559 - (22%)
• Similarity: 229/559 - (40%)
• Gaps: 86/559 - (15%)

  Fly    22 ILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFEL 86
            :|||.....|.::.|.......:.|..||||..|||:|....|:.:..:.|:.:|.:.||.:|.:
Mouse     6 LLLVAILAFLSVMVLVSVWQQKIRGKLPPGPIPLPFIGNYLQLNRKDVYSSITQLQEHYGPVFTI 70

  Fly    87 KMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLK 149
            .:|....|||.....|::..  ..:..:||......:.:..|:|:..:..:..:..||.:|..||
Mouse    71 HLGPRRVVVLYGYDAVKEALEDNAEEFSGRGEQATFNTLFKGYGVTFSNGERAKQLRRFSIATLK 135

  Fly   150 ALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITY 214
            ..|:.:|      .:|.||.......:::.    :.:|.:.::|...|..::.|:|:.:|||..:
Mouse   136 DFGLGKR------GMEERIQEEAGCLIKML----QGTCGAPIDPTMYLSKTVSNVISSIVFGDRF 190

  Fly   215 KRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACG 279
            ..:|.::|.|.::..:                :....|            :.|..:||.......
Mouse   191 NYEDKEFLSLLQMMSQ----------------MNQFAA------------SPTGQLYDMFHSVMK 227

  Fly   280 QRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKE----ADPSQEQSEADEDDEESDEEDTYEPECI 340
            .....:|::.|:       ..:||...:::.|.    .||:                   .|...
Mouse   228 YLPGPQQQIIKD-------SHKLEDFMIQKVKHNHSTLDPN-------------------SPRGF 266

  Fly   341 LEHFLAVRDTDSQLYCDDQLRHLL---ADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHE---L 399
            ::.||.....:.....:..:::|:   .:||.||.:|..:.||:..|.|.:....:.::||   .
Mouse   267 IDSFLIHMQKEKNFNSEFHMKNLVMTSLNLFFAGSETVSSLLRYGFLLLMKHPDVEAKVHEEIDR 331

  Fly   400 LLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAI 464
            ::.....|..|:...:.|.:|.|.|..|..:..|||||....::.....:|:..|:.:.....::
Mouse   332 VIGRNRQPQYEDHMKMPYTQAVIHEIQRFSNFAPLGIPRRITKDTSFRGFFLPKGTDVFPIMGSL 396

  Fly   465 HMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLE 529
            .:||..|..|::|.|:.||...|..:..|.|:|||.|.|.|.|..:.:|.|.||...||:.|..:
Mouse   397 MIDPKFFSSPKDFNPQHFLDDKGQLKKIPAFLPFSIGKRSCLGYSLGKMQLFLFFTTILQNFRFK 461

  Fly   530 LPSGTEVDMAGESGITLTPTPHMLRFTK-LPAVEMRHAP 567
            .|...|       .|..:|.|.  .||: :|...|...|
Mouse   462 FPRKLE-------DINESPKPE--GFTRIIPKYTMSFVP 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	114/517 (22%)
Cyp2a22	NP_001094937.1	p450	33..489	CDD:278495	118/528 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000