Protein Alignment phtm and Cyp2c23

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_017173651.1
• Gene: Cyp2c23 / 226143
• MGIID: 1888897
• Length: 501
• Species: Mus musculus
• Alignment Length: 556
• Identity: 148/556 - (26%)
• Similarity: 242/556 - (43%)
• Gaps: 86/556 - (15%)

  Fly    19 SLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGI 83
            :|::|::..:|.|:.::...|    ..|..||||..||.:|.:..||.:....||.||||.||.:
Mouse     8 TLALLVLVMSLSLLSVWTKMR----TGGRLPPGPTPLPIIGNILQLDLKDIPASLSKLAKEYGPV 68

  Fly    84 FELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETID 146
            :.|..|..|||||....:|::..  :.|...||.||.:......|.||:.::.:.|:..||.::.
Mouse    69 YTLYFGSWPTVVLHGYDVVKEALLNQGDEFLGRGPLPIIEDSQKGHGIVFSEGERWKLLRRFSLM 133

  Fly   147 WLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFG 211
            .||..||.:|      .||.|    |.|..|....|..|:.|...:|...|..:..|:|..::|.
Mouse   134 TLKNFGMGKR------SLEER----VQEEARCLVEELHKTEAQPFDPTFILACAPCNVICSILFN 188

  Fly   212 ITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPW---LRHLPANVRNIRFLLEGKAKTHAIYDR 273
            ..:..:|..:|.|..|..:....:....:..:..|   ::::|...|.....|.|      :.:.
Mouse   189 ERFPYNDKTFLNLMDLLNKNFYQLNSIWIQMYNLWPTIMKYIPGKHREFSKRLGG------VKNF 247

  Fly   274 IVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPE 338
            |:|    ::||.|                        :..||:..:...|
Mouse   248 ILE----KVKEHQ------------------------ESLDPANPRDYID--------------- 269

  Fly   339 CILEHFLAVRDTDSQLYCDDQLRHLL---ADLFGAGVDTSLATLRWFLLYLAREQRCQ------- 393
            |.|.   .:.:....|..|..|.:|.   ::||.||.:|:..|||:.||.|.:....|
Mouse   270 CFLS---KIEEEKHNLKSDFNLENLAICGSNLFTAGTETTSTTLRFGLLLLVKHPEVQGTPSEEG 331

  Fly   394 RRLHELL---LPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGS 455
            .::||.|   :.....|::::...|.|..|.:.|..|..:::|..:||...::.....|.|..|:
Mouse   332 AKVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRHYVIPKGT 396

  Fly   456 MIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTG 520
            .:.....:|.:|...||.||:|.|..||..:|.::....|:|||.|.|.|.||.:|||.|.||..
Mouse   397 AVFPFLSSILLDQKEFPNPEKFDPGHFLDKNGCFKKTDYFVPFSLGKRSCVGEGLARMELFLFFT 461

  Fly   521 RILRRFHLE-LPSGTEVDMAG-ESGITLTPTPHMLR 554
            .||::|.|: |....::|:.. .:|:...|.|:.||
Mouse   462 TILQKFSLKALVEPKDLDIKPVTTGLFNLPPPYKLR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	124/491 (25%)
Cyp2c23	XP_017173651.1	CYP2C-like	65..496	CDD:410758	125/492 (25%)