Protein Alignment phtm and Cyp2c70

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_663474.2
• Gene: Cyp2c70 / 226105
• MGIID: 2385878
• Length: 489
• Species: Mus musculus
• Alignment Length: 527
• Identity: 132/527 - (25%)
• Similarity: 229/527 - (43%)
• Gaps: 84/527 - (15%)

  Fly    46 GAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFF--RR 108
            |..||||..||.:|.:..:|.:...||:..|||:||.:|.:.:|..|||||.....:::..  :.
Mouse    27 GKLPPGPTPLPIVGNILQVDVKNISKSMGMLAKKYGPVFTVYLGMKPTVVLHGYKAMKEALIDQG 91

  Fly   109 DVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVD 173
            |..:.:....|......|.||:.:..:.|:..||.::..|:::||.::      .:|.||.   :
Mouse    92 DEFSDKTDSSLLSRTSQGLGIVFSNGETWKQTRRFSLMVLRSMGMGKK------TIEDRIQ---E 147

  Fly   174 ECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGV- 237
            |.:.:.|. .:|:..|..:|...|.....|:|:.::|...:..:|..:   |...|...:.|.:
Mouse   148 EILYMLDA-LRKTNGSPCDPSFLLACVPCNVISTVIFQHRFDYNDQTF---QDFMENFHRKIEIL 208

  Fly   238 ----SGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRL 298
                |.:.:..|.|.:|| .:.| |||                             |::.:||:.
Mouse   209 ASPWSQLCSAYPILYYLP-GIHN-RFL-----------------------------KDVTQQKKF 242

  Fly   299 QRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTD----SQLYCDDQ 359
               :.:|..|..|..|.|                   .|:..:::||...:.:    ...:..|.
Mouse   243 ---ILEEINRHQKSLDLS-------------------NPQDFIDYFLIKMEKEKHNQKSEFTMDN 285

  Fly   360 LRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELL---LPLGPSPTLEELEPLAYLRAC 421
            |...:.||||||.:|:.:|:::.||.|.:......::.|.:   :.....||:::...:.|..|.
Mouse   286 LVVSIGDLFGAGTETTSSTVKYGLLLLLKYPEVTAKIQEEIAHVIGRHRRPTMQDRNHMPYTDAV 350

  Fly   422 ISETMRIRSVVPLGIPHGCKENFVVGDYFI-KGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTA 485
            :.|..|....||:..|....::.....|.| ||.|::.|....:: |...||.||:|.|..||..
Mouse   351 LHEIQRYIDFVPIPSPRKTTQDVEFRGYHIPKGTSVMACLTSVLN-DDKEFPNPEKFDPGHFLDE 414

  Fly   486 DGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLE-LPSGTEVDMAG-ESGITLTP 548
            .|.::....|:.||:|.|.|.||.:|||.:.|....||:.|.|: |....::|... ::|:...|
Mouse   415 KGNFKKSDYFVAFSAGRRACIGEGLARMEMFLILTNILQHFTLKPLVKPEDIDTKPVQTGLLHVP 479

  Fly   549 TPHMLRF 555
            .|..|.|
Mouse   480 PPFELCF 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	115/488 (24%)
Cyp2c70	NP_663474.2	CYP2C-like	61..484	CDD:410758	116/489 (24%)