Protein Alignment phtm and cyp-14A2

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_510204.1
• Gene: cyp-14A2 / 187184
• WormBaseID: WBGene00010706
• Length: 492
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 137/564 - (24%)
• Similarity: 238/564 - (42%)
• Gaps: 111/564 - (19%)

  Fly    20 LSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            :|||:| ..||.:.:|:......  :...|.||:.|||:|.:..:.:....:.|..|:|.||..|
 Worm     1 MSILIV-AFLVSITVYIAYFYWK--VSKYPKGPFPLPFIGNILQIPSENIQEYLDDLSKTYGPCF 62

  Fly    85 ELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLY-------------LTHGIMGGFGIICAQEDI 136
            .| ...:|.:||:|...|::.|   |..|.|.:|             |..|::...|      |.
 Worm    63 TL-WTPLPAIVLTDYEHVKEAF---VTQGDAFIYRADRPPETLLQPHLNTGVLFSNG------DN 117

  Fly   137 WRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSL 201
            ||..||..:..|:..|:.|.      .:|.::.|.|.|.:...:..|.|   ..|:....:...:
 Worm   118 WRFQRRTALKILRDFGLGRN------LMEEQVMRSVHEMLAQLERIADK---KNVDMFWPIQLCV 173

  Fly   202 GNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIG-----VSGVVNFL----PWLRHLPANVRNI 257
            ||:||:.:|...||.:|      .:..|..||::.     |.|...||    |||:|.|
 Worm   174 GNVINESLFSYHYKYED------SKKFETFVKVLDKHLKTVQGKTIFLMSAFPWLKHFP------ 226

  Fly   258 RFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEA 322
               :.|:...|.|                                 |:.::..:|....:..|:.
 Worm   227 ---VIGELGYHRI---------------------------------KKNIQSYQEFINDEVTSQI 255

  Fly   323 DEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLA---DLFGAGVDTSLATLRWFLL 384
            ...|.||      |||..:..::...........|  :.:|.|   |.:.||::|:..:|||.|.
 Worm   256 KHYDGES------EPENFVHAYMQQMKQSGNPNLD--MNNLCASVIDFWLAGMETTSNSLRWHLA 312

  Fly   385 YLAREQRCQRRLH-ELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVV 446
            ::.:....|.::. |:|..:|.:  |::.:...:.|.:|.|.|..|..:::|:...|..:::.::
 Worm   313 FMMKYPEIQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPILGTHTNRDDILL 377

  Fly   447 GDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGA---YQAPPQFIPFSSGYRMCPGE 508
            ....|..|:::....|::..:...|.|..:|.|:|:|.|||.   .....:.||||.|.|.|.||
 Worm   378 KGKKIPTGTLVFAQIWSVLKNDPVFEESSKFNPDRYLMADGKTINKSVLERTIPFSVGKRNCVGE 442

  Fly   509 EMARMILTLFTGRILRRFHLELPSGTEVDMAGESGITLTPTPHM 552
            .:|||.|.|....:::::.. :|. |.:|:....|..||..|::
 Worm   443 GLARMELFLIFSALIQKYEF-IPK-TNIDVKPVCGAVLTTKPYI 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	119/503 (24%)
cyp-14A2	NP_510204.1	CYP1_2-like	59..483	CDD:410710	118/500 (24%)