Protein Alignment phm and CYP2J2

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_000766.2
• Gene: CYP2J2 / 1573
• HGNCID: 2634
• Length: 502
• Species: Homo sapiens
• Alignment Length: 556
• Identity: 143/556 - (25%)
• Similarity: 249/556 - (44%)
• Gaps: 80/556 - (14%)

  Fly    17 VQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYG 81
            |...::||...|.:|...:|..|:..:.    |||||.|||||....:|....|..:|...|:||
Human    16 VHPRTLLLGTVAFLLAADFLKRRRPKNY----PPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYG 76

  Fly    82 GIFELKMGRVPTVVLSDAALVRD-FFRRDVMTGRAPLY-LTHGIMGGFGIICAQEDIWRHARRET 144
            .:|.|::|.:..|:::...|::: ....|...|..|:. :...|....|:|.:....|:..||.|
Human    77 NLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFT 141

  Fly   145 IDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEA-KKSCASEVNPLPALHHSLGNIINDL 208
            :..|:..|:.::      .||.||.   :|...|  ||| |:......:|...:::::.|||..:
Human   142 LTALRNFGLGKK------SLEERIQ---EEAQHL--TEAIKEENGQPFDPHFKINNAVSNIICSI 195

  Fly   209 VFGITYKRDDPDWLYLQRLQEEGVKLIGVS---GVVNFLPW-LRHLPANVRNIRFLLEGKAKTHA 269
            .||..::..|..:..|.:|.:| |..:..|   .:.|..|| ::.||.
Human   196 TFGERFEYQDSWFQQLLKLLDE-VTYLEASKTCQLYNVFPWIMKFLPG----------------- 242

  Fly   270 IYDRIVEACGQRLKEKQKVFKELQEQKR-LQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEED 333
                          ..|.:|...::.|. :...::|.:    |:.:|:          |..|..|
Human   243 --------------PHQTLFSNWKKLKLFVSHMIDKHR----KDWNPA----------ETRDFID 279

  Fly   334 TYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLH- 397
            .|..| :.:|    ....:..:.::.|.....|||.||.:|:..||||.|||:|.....|.::.
Human   280 AYLKE-MSKH----TGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQA 339

  Fly   398 --ELLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCS 460
              :.::..|..|:....|.:.|..|.|.|..|:.:::||.:|.....:..:..|.:..|:||:.:
Human   340 EIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTN 404

  Fly   461 EWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRR 525
            ..|:|.||..:..|:.|.|:.|| .:|.::....|:|||.|.|.|.||::||..|.:|...::::
Human   405 LTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQK 468

  Fly   526 FHLELPSGTEVDMAGESGITLTPTPHMLRFTKLPAV 561
            |....|:..::.:....|||::|..|  |...:|.|
Human   469 FTFRPPNNEKLSLKFRMGITISPVSH--RLCAVPQV 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	133/516 (26%)
CYP2J2	NP_000766.2	p450	44..497	CDD:365848	134/517 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910