Protein Alignment phtm and Cyp2c40

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_034134.3
• Gene: Cyp2c40 / 13099
• MGIID: 1306815
• Length: 491
• Species: Mus musculus
• Alignment Length: 559
• Identity: 142/559 - (25%)
• Similarity: 222/559 - (39%)
• Gaps: 114/559 - (20%)

  Fly    32 VILYLC---------ERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELK 87
            |:|.||         .|| ....|..||||..||.:|....:|.:...:.|...:|.||.:|.|.
Mouse     5 VVLVLCLSFLLVLSLWRQ-RSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLY 68

  Fly    88 MGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKA 150
            .|..|.|||.....:::..  ..:..:||..:.:...:..|.||..:..::|:..|..|::.|:.
Mouse    69 FGSQPIVVLHGYEAIKEALIDHGEEFSGRGRIPVFDKVSTGKGIGFSHGNVWKATRVFTVNTLRN 133

  Fly   151 LGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYK 215
            |||.:          |.|...|.|..:....|.||:..|..:|...:..:..|:|..:||...:.
Mouse   134 LGMGK----------RTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFD 188

  Fly   216 RDDPDWLYLQRLQEEGVKLIGVSG--VVNFLPWL--------RHLPANVRNIRFLLEGKAKTHAI 270
            ..|.|:|.|.....|..:::...|  :.|.:|.|        ..|..|...|:..|.||.|.|
Mouse   189 YKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGSHNKLFKNHTWIKSYLLGKIKEH-- 251

  Fly   271 YDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTY 335
                                                                    |||  .|..
Mouse   252 --------------------------------------------------------EES--LDVT 258

  Fly   336 EPECILEHFLAVRDTDSQL----YCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRL 396
            .|...:::||..|...:.:    |..:.|..|:.||...|.:|..:|:|:.||.|.:......::
Mouse   259 NPRDFIDYFLIQRRQKNGIEHMDYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKV 323

  Fly   397 HELL---LPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPH--GCKENFVVGDYFIKGGSM 456
            .|.:   :....||.:::...:.|..|.:.|..|...:.|.|:.|  .|...|  .:|||..|:.
Mouse   324 QEEIDNVIGRHRSPCMQDRNHMPYTNAMVHEVQRYIDLGPNGVVHEVTCDTKF--RNYFIPKGTQ 386

  Fly   457 IVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGR 521
            ::.|..::..|...||.||.|.|..||..:|.::....|:|||:|.|:|.||.:|||.|.||...
Mouse   387 VMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTT 451

  Fly   522 ILRRFHLE-LPSGTEVDMAGESGITLTPTPHMLRFTKLP 559
            ||:.|.|: |....::||          ||....|:|:|
Mouse   452 ILQNFKLKPLVDPKDIDM----------TPKHSGFSKIP 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	121/493 (25%)
Cyp2c40	NP_034134.3	CYP2C-like	61..485	CDD:410758	125/502 (25%)