Protein Alignment phtm and Cyp2c29

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_031841.3
• Gene: Cyp2c29 / 13095
• MGIID: 103238
• Length: 490
• Species: Mus musculus
• Alignment Length: 562
• Identity: 144/562 - (25%)
• Similarity: 237/562 - (42%)
• Gaps: 103/562 - (18%)

  Fly    22 ILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFEL 86
            :.|....|:|:.|:   ||.:. .|..||||..||.:|....:|.:...:|....:|.||.:|.|
Mouse     7 LALTLSCLILLSLW---RQSSG-RGKLPPGPTPLPIIGNFLQIDVKNISQSFTNFSKAYGPVFTL 67

  Fly    87 KMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLK 149
            .:|..|||:|.....|::..  |.:...||....:...|:.|||::.:..:.|:..||.|:..|:
Mouse    68 YLGSKPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLR 132

  Fly   150 ALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITY 214
            .|||.:|      .:|.|    |.|..:....|.:|:..|..:|...|..:..|:|..::|...:
Mouse   133 NLGMGKR------NIEDR----VQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRF 187

  Fly   215 KRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLR----------HLPAN----VRNIRFLLEGKA 265
            ...|.::|.|.....|.||::.       .|||:          :.|.:    |:|..:|
Mouse   188 DYKDKEFLILMDKINENVKILS-------SPWLQVCNSFPSLIDYCPGSHHKIVKNFNYL----- 240

  Fly   266 KTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESD 330
            |::.:         :::||                  .||.|
Mouse   241 KSYLL---------EKIKE------------------HKESL----------------------- 255

  Fly   331 EEDTYEPECILEHFL----AVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQR 391
              |...|...::::|    .|...:...:..:.|...:.||||||.:|:..|||:.||.|.:...
Mouse   256 --DVTNPRDFIDYYLIKQKQVNHIEQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPD 318

  Fly   392 CQRRLHE---LLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKG 453
            ...::.|   .::....||.:::...:.|..|.|.|..|...::|..:||....:.....|.|..
Mouse   319 VTAKVQEEIDRVVGRHRSPCMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPK 383

  Fly   454 GSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLF 518
            |:.::.|..::..|...||.||.|.|..||..:|.::....|:|||:|.|:|.||.:|||.|.|.
Mouse   384 GTTVITSLSSVLHDSKEFPNPEMFDPGHFLNGNGNFKKSDYFMPFSTGKRICAGEGLARMELFLI 448

  Fly   519 TGRILRRFHLE-LPSGTEVDMAG-ESGITLTPTPHMLRFTKL 558
            ...||:.|.|: |....|:|:.. .:|....|.|:.|.|..|
Mouse   449 LTTILQNFKLKSLVHPKEIDITPVMNGFASLPPPYQLCFIPL 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	123/496 (25%)
Cyp2c29	NP_031841.3	CYP2C-like	61..485	CDD:410758	124/497 (25%)