Protein Alignment phtm and Cyp2b13

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_006539571.1
• Gene: Cyp2b13 / 13089
• MGIID: 88599
• Length: 517
• Species: Mus musculus
• Alignment Length: 572
• Identity: 143/572 - (25%)
• Similarity: 231/572 - (40%)
• Gaps: 128/572 - (22%)

  Fly    12 GWMPSVQSLSILLVPGALVLVILYLCERQCNDLMG---------APPPGPWGLPFLGYLPFLDAR 67
            ||:       ||::.|.|..|  |....|..|:.|         ||               ||
Mouse    43 GWI-------ILMIAGLLRKV--YGAVEQTMDVRGKQNALVIQHAP---------------LD-- 81

  Fly    68 APHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGII 130
                  |:|.:::|.:|.:.:|..|.|||.....:|:..  ..:..:||..:.....:|..:||.
Mouse    82 ------QRLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVNNAEAFSGRGTIAAAQLVMQDYGIF 140

  Fly   131 CAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLP 195
            .:..:.|:..||.::..:|..||.:|..|.|.:.|.       :|:   ..|.||...:.::|..
Mouse   141 FSSGERWKTLRRFSLATMKEFGMGKRSVEERIKEEA-------QCL---VEELKKYQGAPLDPTF 195

  Fly   196 ALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIG---------VSGVVNFLPWL-RHL 250
            .......|||..:|||..:...|..:|.|..|..:...|:.         .||::.:.|.: |.:
Mouse   196 FFQCVTANIICSIVFGERFDYTDEQFLRLLNLMYQIYSLLRSFSCQMFELFSGLLKYFPGVHRQI 260

  Fly   251 PANVRNI-RFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEAD 314
            ..|.:.| .|:      ||.:             ||.:.                       ..|
Mouse   261 AKNQQEILNFI------THRV-------------EKHRA-----------------------TLD 283

  Fly   315 PSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATL 379
            ||          |..|..|||    :|.......:.:::.:..:.:..:|: ||.||.:|:..||
Mouse   284 PS----------EPRDFIDTY----LLRMEKEKSNHNTEFHHQNLMMSVLS-LFFAGTETTSTTL 333

  Fly   380 -RWFLLYLAREQRCQRRLHELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCK 441
             ..|||.|......::...|:...:|..  |||::...:.|..|.|.|..|...:||.|.||...
Mouse   334 CCGFLLMLMYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDIVPTGAPHRVT 398

  Fly   442 ENFVVGDYFI-KGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMC 505
            ::.:...|.: |...:......|:| ||..|.:|:.|.|:.||.|:||.:....|:|||:|.|:|
Mouse   399 KDTMFRGYLLPKNTEVYPILSSALH-DPQYFEQPDSFNPDHFLDANGALKKSEAFLPFSTGKRIC 462

  Fly   506 PGEEMARMILTLFTGRILRRFHLELP-SGTEVDMA-GESGITLTPTPHMLRF 555
            .||.:||..|.||...||:.|.:..| :..::|:. .||||...|..:.:.|
Mouse   463 LGESIARNELFLFFTSILQNFSVASPVASKDIDLTPKESGIGKIPPTYQICF 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	125/490 (26%)
Cyp2b13	XP_006539571.1	CYP2B	88..512	CDD:410765	125/491 (25%)