Protein Alignment phm and Cyp2b10

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_034129.1
• Gene: Cyp2b10 / 13088
• MGIID: 88598
• Length: 491
• Species: Mus musculus
• Alignment Length: 567
• Identity: 145/567 - (25%)
• Similarity: 238/567 - (41%)
• Gaps: 107/567 - (18%)

  Fly    15 PSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKR 79
            |||    :||:  ||::..|.|..|......|..||||..||.||.|..:|.....||..:|.::
Mouse     3 PSV----LLLL--ALLVGFLLLLARGHPKSRGNFPPGPRPLPLLGNLLQMDRGGLLKSFIQLREK 61

  Fly    80 YGGIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARR 142
            ||.:|.:.:|..|.|:|.....:|:..  :.:..:||..:.:.......:|:|.|..:.|:..||
Mouse    62 YGDVFTVHLGPRPVVMLCGTDTIREALVGQAEAFSGRGTVAVVEPTFKEYGVIFANGERWKTLRR 126

  Fly   143 ETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIIND 207
            .::..::..||.:|..|.|          :.|..:....|.:||..:.::|.........|||..
Mouse   127 FSLATMRDFGMGKRSVEER----------IQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICS 181

  Fly   208 LVFGITYKRDDPDWLYLQRLQEEGVKLIG---------VSGVVNFLPWLRHLPANVRNIRFLLEG 263
            :|||..::..|..:|.|..|..:...||.         .||.:.:.|...
Mouse   182 IVFGERFEYTDRQFLRLLELFYQTFSLISSFSSQMFELFSGFLKYFPGAH--------------- 231

  Fly   264 KAKTHAIYDRIVEACGQRLKEKQKVFKELQE-QKRLQRQLEKEQLRQSKEADPSQEQSEAD---- 323
                                  :::.|.||| ...:...:||.:    ...|||..:...|
Mouse   232 ----------------------RQISKNLQELLDYIGHSVEKHR----ATLDPSVPRDFIDIYLL 270

  Fly   324 -EDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRW-FLLYL 386
             .:.|:|::...:..:.::...|:                    ||.||.:||..|||: |||.|
Mouse   271 RMEKEKSNQHTEFHHQNLMMSVLS--------------------LFFAGTETSSTTLRYGFLLML 315

  Fly   387 AREQRCQRRLHELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDY 449
            ......::...|:...:|..  |||::...:.|..|.|.|..|...::|:|:||...::.:...|
Mouse   316 KYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLIPIGVPHRVTKDTMFRGY 380

  Fly   450 FI-KGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARM 513
            .: |...:......|:| ||..|.:|:.|.|:.||.|:||.:....|:|||:|.|:|.||.:||.
Mouse   381 LLPKNTEVYPILSSALH-DPQYFEQPDSFNPDHFLDANGALKKSEAFLPFSTGKRICLGESIARN 444

  Fly   514 ILTLFTGRILRRF----HLELPSGTEVDMA-GESGITLTPTPHMLRF 555
            .|.||...||:.|    |:   :..::|:. .||||...|..:.:.|
Mouse   445 ELFLFFTSILQNFSVASHV---APKDIDLTPKESGIGKIPPTYQICF 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	133/531 (25%)
Cyp2b10	NP_034129.1	p450	42..488	CDD:278495	125/520 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000