Protein Alignment phm and Cyp2a5

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_031838.2
• Gene: Cyp2a5 / 13087
• MGIID: 88597
• Length: 494
• Species: Mus musculus
• Alignment Length: 571
• Identity: 136/571 - (23%)
• Similarity: 235/571 - (41%)
• Gaps: 125/571 - (21%)

  Fly    22 ILLVPGALVLVILYLCE--RQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIF 84
            :|||.....|.:|.|..  :| ..|.|..||||..|||:|....|:....:.||.|:::|||.:|
Mouse     6 LLLVAAVAFLSVLVLMSVWKQ-RKLSGKLPPGPTPLPFIGNFLQLNTEQMYNSLMKISQRYGPVF 69

  Fly    85 ELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWL- 148
            .:.:|....|||.....|::                       .::...|:......:.|.|||
Mouse    70 TIYLGPRRIVVLCGQEAVKE-----------------------ALVDQAEEFSGRGEQATFDWLF 111

  Fly   149 KALGMTRRPGELRARLERRIA-----------RGVDECVR-----LFDTEAKKSCASEVNPLPAL 197
            |..|:....|| ||:..||.:           ||::|.::     |.|: .:|:..:.::|...|
Mouse   112 KGYGVAFSSGE-RAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDS-FRKTNGAFIDPTFYL 174

  Fly   198 HHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVS-GVV--NFLPWLRHLPANVRNIRF 259
            ..::.|:|:.:|||..:..:|.::|.|.|:.....:....| |.:  .|...::|||.
Mouse   175 SRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSMGQLYEMFSSVMKHLPG------- 232

  Fly   260 LLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADE 324
                                    .:|:.|||||   .|:..:.|:.....:..||:
Mouse   233 ------------------------PQQQAFKELQ---GLEDFITKKVEHNQRTLDPN-------- 262

  Fly   325 DDEESDEEDTYEPECILEHFL-----AVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLL 384
                       .|...::.||     ..::.:::.|..:.:...| :||.||.:|...|||:..|
Mouse   263 -----------SPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTL-NLFFAGTETVSTTLRYGFL 315

  Fly   385 YLAREQRCQRRLHE---LLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVV 446
            .|.:....:.::||   .::.....|..|:...:.|..|.|.|..|...::|:|:.....::...
Mouse   316 LLMKHPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKF 380

  Fly   447 GDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMA 511
            .|:.:..|:.:.....::..||..|..|::|.|:.||...|.::....|:|||.|.|.|.||.:|
Mouse   381 RDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKNDAFVPFSIGKRYCFGEGLA 445

  Fly   512 RMILTLFTGRILRRFHL---ELPSGTEVDMAGESGITLTPTPHMLRFTKLP 559
            ||.|.||...|::.||.   :.|...:|            :|.::.|..:|
Mouse   446 RMELFLFLTNIMQNFHFKSTQAPQDIDV------------SPRLVGFATIP 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	125/536 (23%)
Cyp2a5	NP_031838.2	p450	34..491	CDD:278495	127/542 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000