Protein Alignment phm and Cyp2c50

DIOPT Version :9

• Sequence 1: NP_001285414.1
• Gene: phm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_598905.2
• Gene: Cyp2c50 / 107141
• MGIID: 2147497
• Length: 490
• Species: Mus musculus
• Alignment Length: 548
• Identity: 150/548 - (27%)
• Similarity: 238/548 - (43%)
• Gaps: 89/548 - (16%)

  Fly    29 LVLVILYLC------ERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELK 87
            ||||....|      .||.:: .|..||||..||.:|.:..::.:...:|...|:|.||.::.|.
Mouse     5 LVLVFTLSCLFLLSLWRQSSE-RGKLPPGPTPLPIIGNILQINVKDICQSFTNLSKVYGPVYTLY 68

  Fly    88 MGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKA 150
            :||.|||||.....|::..  ..:...||..|.:......|.|||.::.::|::.||.::..|:.
Mouse    69 LGRKPTVVLHGYEAVKEALVDHGEEFAGRGRLPVFDKATNGMGIIFSKGNVWKNTRRFSLTTLRN 133

  Fly   151 LGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYK 215
            |||.:|..|.|          |.|..|....|.:|:..|..:|...|..:..|:|..::|...:.
Mouse   134 LGMGKRSIEDR----------VQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICSIIFQDRFD 188

  Fly   216 RDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRN-IRFLLEGKAKTHAIYDRIVEACG 279
            ..|.|:|.|.....|..|::..       |||:     |.| ...||:....:|
Mouse   189 YKDRDFLNLMEKLNEITKIMST-------PWLQ-----VCNTFPVLLDYCPGSH----------- 230

  Fly   280 QRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHF 344
                  .||||.....|..  .|||.:                    |..:..|...|...:::|
Mouse   231 ------NKVFKNYACIKNF--LLEKIK--------------------EHEESLDVTIPRDFIDYF 267

  Fly   345 LAVRDTDSQLY-CDDQLRHL---LADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELL---LP 402
            |.....::..| ..::|.||   :.|||.||.:|:..|||:.||.|.:......::.|.:   :.
Mouse   268 LINGGQENGNYPLKNRLEHLAITVTDLFSAGTETTSTTLRYALLLLLKYPHVTAKVQEEIEHVIG 332

  Fly   403 LGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMD 467
            ....|.:::...:.|..|.|.|..|...:||..:||....:....:|||..|:.::.|..::..|
Mouse   333 KHRRPCMQDRSHMPYTDAMIHEVQRFIDLVPNSLPHEVTCDIKFRNYFIPKGTNVITSLSSVLRD 397

  Fly   468 PVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLE-LP 531
            ...||.||:|.|..||..:|.::....|:|||:|.|:|.||.:|||.|.||...||:.|:|: |.
Mouse   398 SKEFPNPEKFDPGHFLDENGKFKKSDYFMPFSTGKRICAGEGLARMELFLFLTSILQNFNLKPLV 462

  Fly   532 SGTEVDMAGESGITLTPTPHMLRFTKLP 559
            ...::|:          ||.::....:|
Mouse   463 HPKDIDV----------TPMLIGLASVP 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	141/516 (27%)
Cyp2c50	NP_598905.2	p450	30..487	CDD:278495	142/522 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000