DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment phm and cyp2aa7

DIOPT Version :9

Sequence 1:	NP_001285414.1	Gene:	phm / 32857	FlyBaseID:	FBgn0004959	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_001103192.1	Gene:	cyp2aa7 / 101882126	ZFINID:	ZDB-GENE-071004-48	Length:	499	Species:	Danio rerio

Alignment Length:	548	Identity:	152/548 - (27%)
Similarity:	236/548 - (43%)	Gaps:	88/548 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGI 83
            |:.:.|..|.:.||:..:.  :.|...|..||||..|||:|.||. ..:.|.:.::.: .:||.:
Zfish    12 SVGLTLFLGLIFLVLFEIF--RINSYKGRFPPGPTPLPFVGNLPH-SLKNPMEFIRSM-PQYGEM 72

  Fly    84 FELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGIMGGFGIICAQ-EDIWRHARRETIDW 147
            ..:.:||.|.:||:...|.::.|.:|..:||..|.:...:..|.|||... ...||..||..:..
Zfish    73 TTMYLGRRPAIVLNTIQLAKEAFVQDAFSGRPFLPVMDWVANGLGIIMVTFNHSWRQQRRFALHT 137

  Fly   148 LKALGMTRRPGELRARLERR--IARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVF 210
            |:..|:.::..|.|...|.|  ||            |..|.....::|...:.:::.|||..:||
Zfish   138 LRNFGLGKKSVEDRVLEESRYLIA------------EILKGEGKPMSPHHPIQNAVSNIICSIVF 190

  Fly   211 GITYKRDDPDWLYLQRLQEEGVKLIGVSG--VVNFLPWLRHLPA-------NVRNIRFLLEGKAK 266
            |..:..|:..:.||..|..|...|.|.:.  :.|..|:::|.|.       |...:...::|:.|
Zfish   191 GDRFDYDNKRFEYLLELLNENFVLTGSAAGQIFNLAPFIKHFPGPHQKIKQNANELLAFIQGEVK 255

  Fly   267 THAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDE 331
            .|                                         .|..||          |...|.
Zfish   256 EH-----------------------------------------KKTLDP----------DSPRDF 269

  Fly   332 EDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRL 396
            .|.|    :||......:.||..: :..|....||||.||.||:..|:||.||:|.:....|.|.
Zfish   270 IDAY----LLEIEKQKSNKDSTFH-EGNLAISTADLFLAGTDTTSTTIRWGLLFLTQNPDVQERC 329

  Fly   397 H-ELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIV 458
            | |::..||..  |::::.:.|.|..|.:.|..|..::||.|:.|...:...:..|.|..|::::
Zfish   330 HEEIVQVLGYDRLPSMDDRDKLPYTLATVHEIQRCANLVPFGVIHETIQPTKLRGYDIPQGTVVM 394

  Fly   459 CSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRIL 523
            .:..||..|...:..|:.|.||.||..:..:..|..|||||.|.|.|.||.:|:|.|.||...:|
Zfish   395 TNLAAILSDKEHWKHPDTFNPENFLDENRQFSKPESFIPFSLGLRFCLGETLAKMELFLFITSLL 459

  Fly   524 RRFHLELPSGTE-VDMAGESGITLTPTP 550
            :|.|...|...: :||.|..||...|.|
Zfish   460 QRIHFSSPPDAKPIDMDGVVGIVRYPQP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phm	NP_001285414.1	p450	49..555	CDD:278495	145/518 (28%)
cyp2aa7	NP_001103192.1	p450	40..491	CDD:278495	145/518 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.000