Protein Alignment phtm and cyp2a6.5

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_004917147.1
• Gene: cyp2a6.5 / 101730237
• XenbaseID: XB-GENE-22064360
• Length: 493
• Species: Xenopus tropicalis
• Alignment Length: 572
• Identity: 144/572 - (25%)
• Similarity: 234/572 - (40%)
• Gaps: 103/572 - (18%)

  Fly     4 DIVDIGHTGWMPSVQSLSILLVPGALVLVI-----LYLCERQCNDLMGAPPPGPWGLPFLGYLPF 63
            |:..:|           :||||..:.||:.     .|    |.::|    ||||..||.:|.|..
 Frog     2 DVTGLG-----------TILLVLISCVLIFSSWKTFY----QKHNL----PPGPTPLPLMGNLMN 47

  Fly    64 LDARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGG 126
            :.......||.||.::||.::.|..|..|.:||.....|::..  :.:....|..:.....:..|
 Frog    48 IKKGKLVSSLMKLWEQYGAVYTLYFGTQPVIVLCGYDAVKEALVDQAEAFGARGKISSLDPVTQG 112

  Fly   127 FGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEV 191
            :||..:..:.||..|..|:..|:..||.::      .:|.:|.   :|.:.|.: |.:||....:
 Frog   113 YGIGFSNGERWRQMRHFTLKALRDYGMGKK------SIEEKIQ---EEALCLVE-EFRKSGEMPI 167

  Fly   192 NPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIG--VSGVVNFLPWL-RHLPAN 253
            ||...:..::.||...::.|..::.::..:..|....||...|:.  .|.:.|.||.| .::|..
 Frog   168 NPSTHIMKAVANIFFSIMLGNRFEYNNETFSALLATLEEMYTLMNNTWSQIENVLPKLMAYIPGP 232

  Fly   254 VRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQE 318
            .:          |..|:...::....:|:|..|:.|                        |||..
 Frog   233 HK----------KRDALAKELILFFHERVKANQETF------------------------DPSAP 263

  Fly   319 QSEADE-----DDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLAT 378
            :...||     :.|:.:....:....||..|.::                    |..|.:||..|
 Frog   264 RDFIDEFLIKMEQEKKNPNSEFTMRNILMTFFSI--------------------FIGGTETSTTT 308

  Fly   379 LRWFLLYLAREQRCQRRLH-ELLLPLGPSPT--LEELEPLAYLRACISETMRIRSVVPLGIPHGC 440
            |:..||.|.:....|.:|| |:...:|.:.|  |.:...:.|:.|.|:|..|...:.||.:|...
 Frog   309 LKHGLLLLIKYPEIQAKLHMEIDNVIGRNRTVNLNDRNSMPYMEAVINEIQRFSDIAPLNLPRKV 373

  Fly   441 KENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMC 505
            .::.....|.|...:.|......:|.|...|..|.||.|..||...|.::.....:.||:|.|||
 Frog   374 TKDVQFRGYCIPKDTEIYPLLCTVHRDAKYFSSPYEFNPSHFLDEQGRFKKNDALMAFSAGKRMC 438

  Fly   506 PGEEMARMILTLFTGRILRRFHLELPSG-TEVDMAGE-SGITLTPTPHMLRF 555
            |||.:|||.|.||...||:.|.|..|:. ||.|:|.: :||...|..:...|
 Frog   439 PGESLARMELFLFFTTILQNFTLTSPTHFTEDDVAPKMTGIINHPIQYKASF 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	119/486 (24%)
cyp2a6.5	XP_004917147.1	CYP2	64..487	CDD:410652	120/486 (25%)