Protein Alignment phtm and cyp2a6

DIOPT Version :10

• Sequence 1: NP_573319.1
• Gene: phtm / 32857
• FlyBaseID: FBgn0004959
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001120541.1
• Gene: cyp2a6 / 100145695
• XenbaseID: XB-GENE-5903934
• Length: 495
• Species: Xenopus tropicalis
• Alignment Length: 548
• Identity: 144/548 - (26%)
• Similarity: 241/548 - (43%)
• Gaps: 96/548 - (17%)

  Fly    21 SILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFE 85
            :|||  ...|:::|||.:.:........||||...|.||..|.:..|....|..:|:|.||.::.
 Frog     8 TILL--SVCVIILLYLVKWRGKSKSKNLPPGPTAYPLLGNFPQIGLREIPSSFVQLSKTYGPVYT 70

  Fly    86 LKMGRVPTVVLSDAALVRDFF--RRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWL 148
            |.:|....:||.....|::..  :.||.:.|..|.::..:....|:|.:..:.|:..||.|:..|
 Frog    71 LYLGGHRLIVLIGHDAVKEALIDQSDVFSDRGRLGISQVLFDEHGVIMSNGERWKTMRRFTLTTL 135

  Fly   149 KALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGIT 213
            :..||.:|..|.|.:.|   ||.::|..|       |......:|:..|..::.|||..::||..
 Frog   136 RNFGMGKRSVEERIQEE---ARSLEEAFR-------KKKDEPFDPVNLLGPAVSNIICSIIFGDR 190

  Fly   214 YKRDDPDWLYLQRLQEEGVKLIG--VSGVVNFLPWL-RHLPANVRNIRFLLEGKAKTHAIYDRIV 275
            :..:|..:..|.:...|.:.|:.  ...:||..|.| :|:|...:||          ...:::|
 Frog   191 FDYEDEKFTTLLKCMRELINLLNSLFGQLVNVFPNLSQHIPGPHQNI----------FTYFNKI- 244

  Fly   276 EACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPEC- 339
                     ||.|                                    .||....:||.:..|
 Frog   245 ---------KQFV------------------------------------KDEAKSHKDTLDANCP 264

  Fly   340 --ILEHFLAVRDTDSQL-----YCDDQLRHLLADLFGAGVDTSLATLRW-FLLYLAREQRCQRRL 396
              .::.|| :|..:.::     :.:|.|..::.|||.||.:||..|||: ||::|...:..::..
 Frog   265 RDFIDCFL-IRMEEEKMNPNTEFHNDNLFAVIFDLFFAGTETSSLTLRYAFLIFLKYPEVQEKVY 328

  Fly   397 HELLLPLGPS--PTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVC 459
            .|:...:|.:  |:.|:...:.|..|.|.|..|...:||.|:.|...::.....|.|..|:.:..
 Frog   329 KEIDQVIGQNRYPSFEDKIKMPYTEAVIHEVQRFADIVPTGLEHKTSKDTTFRGYDIPKGTSVFP 393

  Fly   460 SEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILR 524
            ...::..||..|..|::|.|..||..:|.::....|:|||:|.|||.||.:|||.|.:|...||:
 Frog   394 VLTSVLKDPKYFKNPDQFDPGHFLDENGCFKKNDAFMPFSAGKRMCAGEGLARMELFIFLTSILQ 458

  Fly   525 RFHLE--LPSGTEVDMAGESGITLTPTP 550
            :|.|:  :|:.|         |.:||.|
 Frog   459 KFTLKPTVPAET---------IKITPQP 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtm	NP_573319.1	CYP306A1-like	81..553	CDD:410745	124/488 (25%)
cyp2a6	NP_001120541.1	cytochrome_P450	65..489	CDD:477761	125/489 (26%)