Protein Alignment CG6696 and TLL2

DIOPT Version :10

• Sequence 1: NP_573318.1
• Gene: CG6696 / 32856
• FlyBaseID: FBgn0030947
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_036597.1
• Gene: TLL2 / 7093
• HGNCID: 11844
• Length: 1015
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 69/223 - (30%)
• Similarity: 113/223 - (50%)
• Gaps: 32/223 - (14%)

  Fly   101 ERLTWPEAAVPFYIDPQDFNANQTMVILKAFKEYHDRTCIRFRPYEQGDKH-WLLIKGNYSGCWS 164
            ||: ||...:| |:...:|..:|..:..:|.:.:...||:.|  .|:.|:. :::......||.|
Human   156 ERI-WPGGVIP-YVIGGNFTGSQRAIFKQAMRHWEKHTCVTF--IERTDEESFIVFSYRTCGCCS 216

  Fly   165 SVGRRSGG-QVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERDEYVKINWENILDGHAHNFNK 228
            .||||.|| |.:::. ..|...|:|.|||.|.:||:|:.:..:||::|.|..|||..|..:||.|
Human   217 YVGRRGGGPQAISIG-KNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLK 280

  Fly   229 YARTHITNFGVEYDYQSVMHYSSRAFSK-------------NGKATIEPLDPYASLGQRRGLSDK 280
            .....:::.|..||:.|:|||:...||:             ||   :.|     ::|||..||..
Human   281 MEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNG---VRP-----TIGQRVRLSQG 337

  Fly   281 DVSKLNEMYE-QDCSEDYLLNFDRFGNY 307
            |:::..::|: ..|.|...   |..||:
Human   338 DIAQARKLYKCPACGETLQ---DTTGNF 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	59/193 (31%)
TLL2	NP_036597.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..49
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..130
		ZnMc_BMP1_TLD	150..349	CDD:239808	64/205 (31%)
		CUB	351..460	CDD:395345	5/15 (33%)
		CUB	464..573	CDD:395345
		FXa_inhibition	580..616	CDD:464251
		CUB	620..729	CDD:395345
		FXa_inhibition	736..771	CDD:464251
		CUB	776..885	CDD:395345
		CUB	889..1002	CDD:395345