DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6696 and astl2c

DIOPT Version :9

Sequence 1:	NP_573318.1	Gene:	CG6696 / 32856	FlyBaseID:	FBgn0030947	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001037864.1	Gene:	astl2c / 594901	XenbaseID:	XB-GENE-6449741	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	221	Identity:	83/221 - (37%)
Similarity:	125/221 - (56%)	Gaps:	18/221 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 EGDIMLHRELLRNGLLNERLTWPEAA-----VPFYIDPQDFNANQTMVILKAFKEYHDRTCIRFR 143
            :|||.  .:..|:.:..:...||:.:     ||:.|. .|::.|:..:|:.|.:|:...||::|.
Frog    60 QGDIA--HKFSRSAINCKECLWPKDSNGIVNVPYTIS-SDYSQNEASLIMAAMQEFATLTCVQFI 121

  Fly   144 PYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALGFYHQQSATERD 208
            |  |.|:...:......||||.:|...|.|.::|....|:.:||:.|||.|.|||.|:.|.::||
Frog   122 P--QTDEDDYIAIQPLDGCWSYIGVNGGAQQVSLGKGGCIYYGVIQHELNHVLGFVHEHSRSDRD 184

  Fly   209 EYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSK-NGKATIEPLDPYAS-- 270
            .||.||::.|...:...|:|   ....|.|:||||.|||||...::|. .||.||.|: |.|:
Frog   185 NYVHINYQYISPDNIAFFDK---KDTDNLGLEYDYSSVMHYPGYSYSNTTGKNTIVPI-PNANVP 245

  Fly   271 LGQRRGLSDKDVSKLNEMYEQD-CSE 295
            :|||.|||..||||:|.:|:.| ||:
Frog   246 IGQRYGLSTLDVSKINRLYQCDVCSK 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6696	NP_573318.1	Astacin	104..295	CDD:279708	78/199 (39%)
CG6696	NP_573318.1	ZnMc_astacin_like	110..289	CDD:239807	73/181 (40%)
astl2c	NP_001037864.1	ZnMc_hatching_enzyme	84..266	CDD:239810	74/188 (39%)
		Astacin	89..266	CDD:279708	74/183 (40%)
		CUB	270..380	CDD:238001	1/2 (50%)
		CUB	383..495	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4121
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.050