DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6696 and MEP1A

DIOPT Version :10

Sequence 1:NP_573318.1 Gene:CG6696 / 32856 FlyBaseID:FBgn0030947 Length:324 Species:Drosophila melanogaster
Sequence 2:XP_011512930.1 Gene:MEP1A / 4224 HGNCID:7015 Length:774 Species:Homo sapiens


Alignment Length:233 Identity:91/233 - (39%)
Similarity:137/233 - (58%) Gaps:16/233 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 SDTNIWEHCGLFEGDIMLHRELLRNGLL--NERLTWPEAAVPFYIDPQDFNANQTMVILKAFKEY 134
            |:.|:.....||:|||:|.:.  ||||.  |.|.|:|   :| ||...:...|....||.||:.:
Human    72 SEINLAAGLDLFQGDILLQKS--RNGLRDPNTRWTFP---IP-YILADNLGLNAKGAILYAFEMF 130

  Fly   135 HDRTCIRFRPYEQGDKHWLLIKGNYSGCWSSVGRRSGGQVLNLNTPKCVTHGVVVHELLHALGFY 199
            ..::|:.|:||| |:..:::.: .:.||||.||.:..||.:::. ..|....::.||:|||||||
Human   131 RLKSCVDFKPYE-GESSYIIFQ-QFDGCWSEVGDQHVGQNISIG-QGCAYKAIIEHEILHALGFY 192

  Fly   200 HQQSATERDEYVKINWENILDGHAHNFNKYARTHITNFGVEYDYQSVMHYSSRAFSKNGKA-TIE 263
            |:||.|:||:||.|.|:.||.|:.|||:.|..:.||:....|||:|:|||...:|:||... ||.
Human   193 HEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTIT 257

  Fly   264 PLDP--YASLGQRRGLSDKDVSKLNEMYEQDCSEDYLL 299
            ...|  .:.:|||...|..|:.:||.||  :|:..:.|
Human   258 AKIPEFNSIIGQRLDFSAIDLERLNRMY--NCTTTHTL 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6696NP_573318.1 ZnMc_astacin_like 110..289 CDD:239807 71/181 (39%)
MEP1AXP_011512930.1 ZnMc_meprin 58..287 CDD:239809 89/225 (40%)
MAM 292..459 CDD:214533 1/2 (50%)
MATH_Meprin_Alpha 459..622 CDD:239752
EGF 702..736 CDD:394967
Blue background indicates that the domain is not in the aligned region.

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